Molecular evolution and retrospective detection of Porcine circovirus 3 in pig production

Detalhes bibliográficos
Ano de defesa: 2018
Autor(a) principal: Saraiva, Giuliana Loreto
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
Idioma: eng
Instituição de defesa: Universidade Federal de Viçosa
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: http://www.locus.ufv.br/handle/123456789/24783
Resumo: The pork industry has increased significantly over the last decades due to the increased consumption of this source of animal protein. The pressure for better efficiency and production has led to an increased production and intensification of international trade and genetic resources. Concurrently with the growth of the pork industry, the diseases present in pig farming have never been so diversified and the number of reports of emerging pathogens has increased significantly over the past 30 years. Considering this information, the present study aimed to conduct a retrospective study of detection and analyze the molecular evolution of an emerging virus in the pork industry, the Porcine circovirus 3 (PCV3). For the retrospective study of PCV3 detection in Brazil, laboratory-stored DNA samples were used for the detection of the virus by the conventional PCR technique. After sequencing the positive samples, phylogenetic and molecular analyzes were performed to understand the epidemiology of PCV3 in Brazil. In addition, phylogenetic analyzes and comparative genomics were conducted to find a possible evolutionary origin of PCV3. The results of this study provided important information about PCV3, which would serve as a basis for the development of control and prevention measures.