Função pulmonar em pacientes asmáticos com Síndrome da Apneia Obstrutiva do Sono: um estudo observacional transversal

• Ano de defesa: 2016
• Autor(a) principal: Fransolin, Carolina [UNIFESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: asthma; obstructive sleep apnea syndrome; pulmonary function; asma; síndrome da apneia obstrutiva do sono; função pulmonar
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=3977811; https://repositorio.unifesp.br/handle/11600/46271

Context. Asthma and Obstructive Sleep Apnea Syndrome are diseases which compromise respiratory function and interfere in lung mechanics as well as the quality of sleep. OSAS is a major factor in asthma exacerbations, it is necessary to investigate the relationship between asthma and OSA through examinations which assess and promote effective responses to questions. Objective. To evaluate and compare the pulmonary functional impairment through the variables Peak Expiratory Flow (PEF), Forced Expiratory Volume in the first second (FEV1), and Forced Vital Capacity (FVC). To evaluate and compare the daytime sleepiness in a sample of patients with asthma attack with OSAS and without OSAS in the emergency room and after 7 days of treatment. Methods. Sixty patients in asthma attacks moderate or severe, we included 24 patients who sought the emergency and emergency service of the São Paulo Hospital of the Escola Paulista de Medicina of the Federal University of São Paulo. Initially, PEF values less than 50% of the product according to age, height and sex were indispensable for the insertion of the patients in the research. Subsequently, all patients underwent pulmonary function tests in the initial 30 minutes in the emergency room after 4 hours and on return after 7 days. Sleepiness scales (Stanford Sleepiness Scale - SSS and Epworth Sleepiness Scale - ESS) were filled at the initial care and at 7-day follow-up. The polysomnography to diagnose the presence of OSAS was performed after 15 days of treatment. Results. The values of PEF, FEV1 and FVC of asthmatic patients with OSAS were lower when compared to asthmatic patients without OSAS at the initial evaluation (emergency room) and after seven days of follow-up (p <0.05). Patients with OSAS did not improve drowsiness after 7 days, but after the same period, patients without OSAS presented improvement in sleepiness, as measured by the Stanford scale. Asthmatic patients with OSAS were older than asthmatic patients without OSAS Conclusion. Asthmatic patients with OSA have greater impairment of lung function than asthmatic patients without OSA. Patients with OSA did not improvement in sleepiness after 7 days of treatment. Patients with OSA is older than patients without OSA.