Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines

Bibliographic Details
Main Author: Guimarães, Bárbara S. G.
Publication Date: 2024
Other Authors: Sousa, Maria João, Gonçalves, M. Sameiro T.
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://hdl.handle.net/1822/94805
Summary: The synthesis and full characterization of new hydroxyl benzo[a]phenoxazinium chlorides with N-(di)propyl and/or N-isopropyl groups in the 5 and 9 positions are described. Photophysical studies carried out in ethanol and water revealed strong absorbances and significant fluorescence emissions at up to 676 nm. The antifungal activity was assessed against Saccharomyces cerevisiae and the results provide possible directions for further studies.
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network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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spelling Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazinesbenzo[a]phenoxazinesNile Blue derivativesfluorescent probesSaccharomyces cerevisiaeThe synthesis and full characterization of new hydroxyl benzo[a]phenoxazinium chlorides with N-(di)propyl and/or N-isopropyl groups in the 5 and 9 positions are described. Photophysical studies carried out in ethanol and water revealed strong absorbances and significant fluorescence emissions at up to 676 nm. The antifungal activity was assessed against Saccharomyces cerevisiae and the results provide possible directions for further studies.This research was funded by Fundação para a Ciência e Tecnologia (FCT) Portugal, by the strategic programmes UID/QUI/0686/2020. Thanks are also due to FCT for financial support to the Portuguese NMR network (PTNMR, Bruker Avance III 400-Univ. Minho).MDPIUniversidade do MinhoGuimarães, Bárbara S. G.Sousa, Maria JoãoGonçalves, M. Sameiro T.2024-10-152024-10-15T00:00:00Zconference paperinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/1822/94805engGuimarães, B. S. G., Sousa, M. J., & Gonçalves, M. S. T. (2024, November 14). Synthesis, Photophysics, and Potential Antifungal Activity of Benzo[a]phenoxazines. ECSOC 2024. MDPI. http://doi.org/10.3390/ecsoc-28-20172cv-prod-432347810.3390/ecsoc-28-20172https://www.mdpi.com/2673-4583/16/1/81info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-02-22T01:19:54Zoai:repositorium.sdum.uminho.pt:1822/94805Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T20:39:17.464679Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines
title Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines
spellingShingle Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines
Guimarães, Bárbara S. G.
benzo[a]phenoxazines
Nile Blue derivatives
fluorescent probes
Saccharomyces cerevisiae
title_short Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines
title_full Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines
title_fullStr Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines
title_full_unstemmed Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines
title_sort Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines
author Guimarães, Bárbara S. G.
author_facet Guimarães, Bárbara S. G.
Sousa, Maria João
Gonçalves, M. Sameiro T.
author_role author
author2 Sousa, Maria João
Gonçalves, M. Sameiro T.
author2_role author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Guimarães, Bárbara S. G.
Sousa, Maria João
Gonçalves, M. Sameiro T.
dc.subject.por.fl_str_mv benzo[a]phenoxazines
Nile Blue derivatives
fluorescent probes
Saccharomyces cerevisiae
topic benzo[a]phenoxazines
Nile Blue derivatives
fluorescent probes
Saccharomyces cerevisiae
description The synthesis and full characterization of new hydroxyl benzo[a]phenoxazinium chlorides with N-(di)propyl and/or N-isopropyl groups in the 5 and 9 positions are described. Photophysical studies carried out in ethanol and water revealed strong absorbances and significant fluorescence emissions at up to 676 nm. The antifungal activity was assessed against Saccharomyces cerevisiae and the results provide possible directions for further studies.
publishDate 2024
dc.date.none.fl_str_mv 2024-10-15
2024-10-15T00:00:00Z
dc.type.driver.fl_str_mv conference paper
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/94805
url https://hdl.handle.net/1822/94805
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Guimarães, B. S. G., Sousa, M. J., & Gonçalves, M. S. T. (2024, November 14). Synthesis, Photophysics, and Potential Antifungal Activity of Benzo[a]phenoxazines. ECSOC 2024. MDPI. http://doi.org/10.3390/ecsoc-28-20172
cv-prod-4323478
10.3390/ecsoc-28-20172
https://www.mdpi.com/2673-4583/16/1/81
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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