Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines
Main Author: | |
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Publication Date: | 2024 |
Other Authors: | , |
Language: | eng |
Source: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
Download full: | https://hdl.handle.net/1822/94805 |
Summary: | The synthesis and full characterization of new hydroxyl benzo[a]phenoxazinium chlorides with N-(di)propyl and/or N-isopropyl groups in the 5 and 9 positions are described. Photophysical studies carried out in ethanol and water revealed strong absorbances and significant fluorescence emissions at up to 676 nm. The antifungal activity was assessed against Saccharomyces cerevisiae and the results provide possible directions for further studies. |
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Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazinesbenzo[a]phenoxazinesNile Blue derivativesfluorescent probesSaccharomyces cerevisiaeThe synthesis and full characterization of new hydroxyl benzo[a]phenoxazinium chlorides with N-(di)propyl and/or N-isopropyl groups in the 5 and 9 positions are described. Photophysical studies carried out in ethanol and water revealed strong absorbances and significant fluorescence emissions at up to 676 nm. The antifungal activity was assessed against Saccharomyces cerevisiae and the results provide possible directions for further studies.This research was funded by Fundação para a Ciência e Tecnologia (FCT) Portugal, by the strategic programmes UID/QUI/0686/2020. Thanks are also due to FCT for financial support to the Portuguese NMR network (PTNMR, Bruker Avance III 400-Univ. Minho).MDPIUniversidade do MinhoGuimarães, Bárbara S. G.Sousa, Maria JoãoGonçalves, M. Sameiro T.2024-10-152024-10-15T00:00:00Zconference paperinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/1822/94805engGuimarães, B. S. G., Sousa, M. J., & Gonçalves, M. S. T. (2024, November 14). Synthesis, Photophysics, and Potential Antifungal Activity of Benzo[a]phenoxazines. ECSOC 2024. MDPI. http://doi.org/10.3390/ecsoc-28-20172cv-prod-432347810.3390/ecsoc-28-20172https://www.mdpi.com/2673-4583/16/1/81info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-02-22T01:19:54Zoai:repositorium.sdum.uminho.pt:1822/94805Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T20:39:17.464679Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
dc.title.none.fl_str_mv |
Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines |
title |
Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines |
spellingShingle |
Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines Guimarães, Bárbara S. G. benzo[a]phenoxazines Nile Blue derivatives fluorescent probes Saccharomyces cerevisiae |
title_short |
Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines |
title_full |
Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines |
title_fullStr |
Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines |
title_full_unstemmed |
Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines |
title_sort |
Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines |
author |
Guimarães, Bárbara S. G. |
author_facet |
Guimarães, Bárbara S. G. Sousa, Maria João Gonçalves, M. Sameiro T. |
author_role |
author |
author2 |
Sousa, Maria João Gonçalves, M. Sameiro T. |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Guimarães, Bárbara S. G. Sousa, Maria João Gonçalves, M. Sameiro T. |
dc.subject.por.fl_str_mv |
benzo[a]phenoxazines Nile Blue derivatives fluorescent probes Saccharomyces cerevisiae |
topic |
benzo[a]phenoxazines Nile Blue derivatives fluorescent probes Saccharomyces cerevisiae |
description |
The synthesis and full characterization of new hydroxyl benzo[a]phenoxazinium chlorides with N-(di)propyl and/or N-isopropyl groups in the 5 and 9 positions are described. Photophysical studies carried out in ethanol and water revealed strong absorbances and significant fluorescence emissions at up to 676 nm. The antifungal activity was assessed against Saccharomyces cerevisiae and the results provide possible directions for further studies. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-10-15 2024-10-15T00:00:00Z |
dc.type.driver.fl_str_mv |
conference paper |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/1822/94805 |
url |
https://hdl.handle.net/1822/94805 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Guimarães, B. S. G., Sousa, M. J., & Gonçalves, M. S. T. (2024, November 14). Synthesis, Photophysics, and Potential Antifungal Activity of Benzo[a]phenoxazines. ECSOC 2024. MDPI. http://doi.org/10.3390/ecsoc-28-20172 cv-prod-4323478 10.3390/ecsoc-28-20172 https://www.mdpi.com/2673-4583/16/1/81 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
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