New Nile blue derivatives as NIR fluorescent probes and antifungal agents

Bibliographic Details
Main Author: Sousa, Rui P. C. L.
Publication Date: 2019
Other Authors: Ferreira, João C. C., Sousa, Maria João M. F., Gonçalves, M. Sameiro T.
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/1822/73250
Summary: The synthesis of four new Nile Blue derivatives with hydrogen, propyl and/or aminopropyl groups as substituents of the amines of 5- and 9-positions is described. Photophysical properties were evaluated in acidified ethanol and aqueous solution at physiological pH. Antifungal activity is also studied through the obtention of MIC values.
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spelling New Nile blue derivatives as NIR fluorescent probes and antifungal agentsBenzo[a]phenoxazinesNile Blue derivativesNIR fluorescent probesAntifungal agentsThe synthesis of four new Nile Blue derivatives with hydrogen, propyl and/or aminopropyl groups as substituents of the amines of 5- and 9-positions is described. Photophysical properties were evaluated in acidified ethanol and aqueous solution at physiological pH. Antifungal activity is also studied through the obtention of MIC values.Thanks are due to Fundação para a Ciência e Tecnologia (FCT) and FEDER (European Fund for Regional Development)-COMPETE-QRENEU for financial support through the Chemistry Research Centre of the University of Minho (Ref. UID/QUI/00686/2013 and UID/QUI/0686/2016), CBMA (PEst OE/BIA/UI4050/2014) and a PhD grant to J.C.F. (SFRH/BD/133207/2017). The NMR spectrometer Bruker Avance III 400 is part of the National NMR Network (PTNMR) and are partially supported by Infrastructure Project No 022161 (co-financed by FEDER through COMPETE 2020, POCI and PORL and FCT through PIDDAC).MDPIUniversidade do MinhoSousa, Rui P. C. L.Ferreira, João C. C.Sousa, Maria João M. F.Gonçalves, M. Sameiro T.20192019-01-01T00:00:00Zconference paperinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/1822/73250eng10.3390/ecsoc-22-05693https://www.mdpi.com/2504-3900/9/1/65info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-11T06:02:27Zoai:repositorium.sdum.uminho.pt:1822/73250Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T15:39:04.555588Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv New Nile blue derivatives as NIR fluorescent probes and antifungal agents
title New Nile blue derivatives as NIR fluorescent probes and antifungal agents
spellingShingle New Nile blue derivatives as NIR fluorescent probes and antifungal agents
Sousa, Rui P. C. L.
Benzo[a]phenoxazines
Nile Blue derivatives
NIR fluorescent probes
Antifungal agents
title_short New Nile blue derivatives as NIR fluorescent probes and antifungal agents
title_full New Nile blue derivatives as NIR fluorescent probes and antifungal agents
title_fullStr New Nile blue derivatives as NIR fluorescent probes and antifungal agents
title_full_unstemmed New Nile blue derivatives as NIR fluorescent probes and antifungal agents
title_sort New Nile blue derivatives as NIR fluorescent probes and antifungal agents
author Sousa, Rui P. C. L.
author_facet Sousa, Rui P. C. L.
Ferreira, João C. C.
Sousa, Maria João M. F.
Gonçalves, M. Sameiro T.
author_role author
author2 Ferreira, João C. C.
Sousa, Maria João M. F.
Gonçalves, M. Sameiro T.
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Sousa, Rui P. C. L.
Ferreira, João C. C.
Sousa, Maria João M. F.
Gonçalves, M. Sameiro T.
dc.subject.por.fl_str_mv Benzo[a]phenoxazines
Nile Blue derivatives
NIR fluorescent probes
Antifungal agents
topic Benzo[a]phenoxazines
Nile Blue derivatives
NIR fluorescent probes
Antifungal agents
description The synthesis of four new Nile Blue derivatives with hydrogen, propyl and/or aminopropyl groups as substituents of the amines of 5- and 9-positions is described. Photophysical properties were evaluated in acidified ethanol and aqueous solution at physiological pH. Antifungal activity is also studied through the obtention of MIC values.
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-01-01T00:00:00Z
dc.type.driver.fl_str_mv conference paper
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/73250
url http://hdl.handle.net/1822/73250
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.3390/ecsoc-22-05693
https://www.mdpi.com/2504-3900/9/1/65
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv MDPI
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