New Nile blue derivatives as NIR fluorescent probes and antifungal agents
| Main Author: | |
|---|---|
| Publication Date: | 2019 |
| Other Authors: | , , |
| Language: | eng |
| Source: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
| Download full: | http://hdl.handle.net/1822/73250 |
Summary: | The synthesis of four new Nile Blue derivatives with hydrogen, propyl and/or aminopropyl groups as substituents of the amines of 5- and 9-positions is described. Photophysical properties were evaluated in acidified ethanol and aqueous solution at physiological pH. Antifungal activity is also studied through the obtention of MIC values. |
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New Nile blue derivatives as NIR fluorescent probes and antifungal agentsBenzo[a]phenoxazinesNile Blue derivativesNIR fluorescent probesAntifungal agentsThe synthesis of four new Nile Blue derivatives with hydrogen, propyl and/or aminopropyl groups as substituents of the amines of 5- and 9-positions is described. Photophysical properties were evaluated in acidified ethanol and aqueous solution at physiological pH. Antifungal activity is also studied through the obtention of MIC values.Thanks are due to Fundação para a Ciência e Tecnologia (FCT) and FEDER (European Fund for Regional Development)-COMPETE-QRENEU for financial support through the Chemistry Research Centre of the University of Minho (Ref. UID/QUI/00686/2013 and UID/QUI/0686/2016), CBMA (PEst OE/BIA/UI4050/2014) and a PhD grant to J.C.F. (SFRH/BD/133207/2017). The NMR spectrometer Bruker Avance III 400 is part of the National NMR Network (PTNMR) and are partially supported by Infrastructure Project No 022161 (co-financed by FEDER through COMPETE 2020, POCI and PORL and FCT through PIDDAC).MDPIUniversidade do MinhoSousa, Rui P. C. L.Ferreira, João C. C.Sousa, Maria João M. F.Gonçalves, M. Sameiro T.20192019-01-01T00:00:00Zconference paperinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/1822/73250eng10.3390/ecsoc-22-05693https://www.mdpi.com/2504-3900/9/1/65info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-11T06:02:27Zoai:repositorium.sdum.uminho.pt:1822/73250Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T15:39:04.555588Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
| dc.title.none.fl_str_mv |
New Nile blue derivatives as NIR fluorescent probes and antifungal agents |
| title |
New Nile blue derivatives as NIR fluorescent probes and antifungal agents |
| spellingShingle |
New Nile blue derivatives as NIR fluorescent probes and antifungal agents Sousa, Rui P. C. L. Benzo[a]phenoxazines Nile Blue derivatives NIR fluorescent probes Antifungal agents |
| title_short |
New Nile blue derivatives as NIR fluorescent probes and antifungal agents |
| title_full |
New Nile blue derivatives as NIR fluorescent probes and antifungal agents |
| title_fullStr |
New Nile blue derivatives as NIR fluorescent probes and antifungal agents |
| title_full_unstemmed |
New Nile blue derivatives as NIR fluorescent probes and antifungal agents |
| title_sort |
New Nile blue derivatives as NIR fluorescent probes and antifungal agents |
| author |
Sousa, Rui P. C. L. |
| author_facet |
Sousa, Rui P. C. L. Ferreira, João C. C. Sousa, Maria João M. F. Gonçalves, M. Sameiro T. |
| author_role |
author |
| author2 |
Ferreira, João C. C. Sousa, Maria João M. F. Gonçalves, M. Sameiro T. |
| author2_role |
author author author |
| dc.contributor.none.fl_str_mv |
Universidade do Minho |
| dc.contributor.author.fl_str_mv |
Sousa, Rui P. C. L. Ferreira, João C. C. Sousa, Maria João M. F. Gonçalves, M. Sameiro T. |
| dc.subject.por.fl_str_mv |
Benzo[a]phenoxazines Nile Blue derivatives NIR fluorescent probes Antifungal agents |
| topic |
Benzo[a]phenoxazines Nile Blue derivatives NIR fluorescent probes Antifungal agents |
| description |
The synthesis of four new Nile Blue derivatives with hydrogen, propyl and/or aminopropyl groups as substituents of the amines of 5- and 9-positions is described. Photophysical properties were evaluated in acidified ethanol and aqueous solution at physiological pH. Antifungal activity is also studied through the obtention of MIC values. |
| publishDate |
2019 |
| dc.date.none.fl_str_mv |
2019 2019-01-01T00:00:00Z |
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conference paper |
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info:eu-repo/semantics/publishedVersion |
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publishedVersion |
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http://hdl.handle.net/1822/73250 |
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http://hdl.handle.net/1822/73250 |
| dc.language.iso.fl_str_mv |
eng |
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eng |
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10.3390/ecsoc-22-05693 https://www.mdpi.com/2504-3900/9/1/65 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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MDPI |
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MDPI |
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