Detalhes bibliográficos
| Ano de defesa: |
2015 |
| Autor(a) principal: |
Pereira, Patrícia Peres Iucif
 |
| Orientador(a): |
Saraiva, Patrícia Pinto
|
| Banca de defesa: |
Não Informado pela instituição |
| Tipo de documento: |
Tese
|
| Tipo de acesso: |
Acesso aberto |
| Idioma: |
por |
| Instituição de defesa: |
Universidade do Sagrado Coração
|
| Programa de Pós-Graduação: |
Biologia Oral
|
| Departamento: |
Ciências da Saúde e Biológicas
|
| País: |
Brasil
|
| Palavras-chave em Português: |
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| Palavras-chave em Inglês: |
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| Área do conhecimento CNPq: |
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| Link de acesso: |
http://tede2.usc.br:8080/jspui/handle/tede/280
|
Resumo: |
This paperwork objective was to analyze comparatively, through microscopy, the epithelial dysplasia present in the leukoplakia located in the tongue and in other mounth locations. Twenty-nine histological slides have been evaluated at the Oral Pathology Lab at UNIFAL – MG, they were microscopically diagnosed as leukoplakia, 14 of them in the tongue region and the other 15 in other mounth regions. The following tissue structures have been analyzed: epithelial surface thickness and stratification; surface keratin layer; presence and shape of the rete ridges and also cell atypia with the following criteria: basal cell morphology; mitoses; pleomorphism; hyperchromatism,; increased nuclear/cytoplasmic ratios; dyskeratosis and keratin pearl. The following gradations regarding dysplasia have been established: absent, mild, moderate and severe. From the 29 leukoplakia, 20 (68,97%) occurred to men and 9 (31,03%) to women. Age average and standard deviation were 52,96±11,58 years old. Regarding the dysplasia presence and final gradation, we could observe in the tongue region, 5 lesions without dysplasia, 6 with mild dysplasia and 3 of them with moderate dysplasia. In the other oral regions, 5 leukoplakia without dysplasia, 6 with mild dysplasia and 4 with moderate dysplasia. Regarding the mitosis, one of the most important dysplasia criteria, we could notice in the leukoplakia located in the tongue, that 4 injuries didn’t have mitosis, 8 had mild mitosis, 1 had moderate mitosis and 1 had severe mitosis. In other regions in 4 lesions we could also notice that there weren’t mitosis presence; in 7 lesions the mitosis were mild, in 1 lesion the mitosis were moderate, and in 3 lesions they were severe. Despite of finding more severe mitosis in the leukoplakia in the other regions, the final gradation was moderate dysplasia in a similar classification between the leukoplakia no differences between leukoplakia location occurred during this study. |
