Detalhes bibliográficos
| Ano de defesa: |
2009 |
| Autor(a) principal: |
PESSOA, Mariana Cavalcante Pedrosa
 |
| Orientador(a): |
MAIA, Frederico Celso Lyra |
| Banca de defesa: |
D'UTRA-VAZ, Beatriz Berlinck,
ALVES, Leucio Câmara,
SILVA JÚNIOR, Valdemiro Amaro da |
| Tipo de documento: |
Dissertação
|
| Tipo de acesso: |
Acesso aberto |
| Idioma: |
por |
| Instituição de defesa: |
Universidade Federal Rural de Pernambuco
|
| Programa de Pós-Graduação: |
Programa de Pós-Graduação em Ciência Veterinária
|
| Departamento: |
Departamento de Medicina Veterinária
|
| País: |
Brasil
|
| Palavras-chave em Português: |
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| Palavras-chave em Inglês: |
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| Área do conhecimento CNPq: |
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| Link de acesso: |
http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/5779
|
Resumo: |
Currently the demand for insecticides of natural origin it has been growing, mainly because they are biodegradable, thus avoiding contamination of the environment and harm people's health. Among these biopesticides may be out products based on neem (Azadirachta indica L.), tree of Asian origin used for centuries in India for various purposes, and had their properties insecticides discovered just 30 years, when its main component the azadirachtin was isolated. In this context it also includes the Andiroba (Carapa guianensis Aublet), a tree listed more of the Amazon region, whose oil seeds has a great commercial potential and many medicinal properties and is marketed well in the Amazon. Thus, this project aims to study the effects of a product lousiness the basis of extract containing Azadirachta indica L., Carapa guianensis Aublet and Saccharum officinarum L., administered in Wistar rats. The tests were performed in four groups with eight rats, each in accordance with the process of inoculation as follows: ocular (OC), oral (P), subcutaneous (SC), intraperitoneal (IP) and more the control group (C ), consisting of four animals. The macroscopic and microscopic analysis of the kidneys, heart, liver, spleen, stomach and intestine of rats, as well as the achievement of all serum biochemistry (total protein, creatinine,urea, aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase were performed in order to investigate the possible toxic effects caused by the administration of this concentrate. The results of the samples showed only lesions in organs such as liver and spleen in animals of group intraperitoneal and skin of individuals of the group of subcutaneous application. Parameters as creatininina, urea, AST, ALT and alkaline phosphatase were shown to be altered in variousgroups including the control, however, only the AST has been shown to be a safe parameter for assessment. |
