Avaliação clínica, hematológica e bioquímica sérica de cães inoculados experimentalmente, por via intravenosa com extrato bruto de Dirofilaria immitis (Leidy, 1856)

Detalhes bibliográficos
Ano de defesa: 2004
Autor(a) principal: BARBOSA, Marco Antônio Granja lattes
Orientador(a): ALVES, Leucio Câmara
Banca de defesa: MAIA, Frederico Celso Lyra, TEIXEIRA, Miriam Nogueira, RABELO, Silvana Suely de Assis
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal Rural de Pernambuco
Programa de Pós-Graduação: Programa de Pós-Graduação em Ciência Veterinária
Departamento: Departamento de Medicina Veterinária
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Dog
Área do conhecimento CNPq:
Link de acesso: http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/5777
Resumo: Studies were performed in two groups of mixed-breed male dogs containing six (Experimental Group) and two (Control Group) animals which were administered IV a crude, whole-body extract of female heartworms or saline solution respectively. The frequency of clinical signs and shock-like reaction as well as changes in clinical parameters such as electrocardiographic record, RBC and WBC counts, serum alanine amino transferase, aspartate amino transferase, creatine phosphokinase and also urea were monitored. The results had been analyzed by the test of Wilcoxon e Mann-Whitney for Clinical hematological, clinical chemistry and by the test of Fischer to electrocardiographic values respectively. Shock with clinical signs such as the pale color of the visible mucous membranes, respiratory disorders, developed in all crude, whole-body extract inoculated dogs. It was observed a significative difference not only between the lynfocytes count and CPK values but also with RBC and eosinophil count absolute. These results indicated that some products present on whole-body extract of female heartworms might be responsible for the onset of shock in dogs.