Influência de polímeros bioadesivos sobre o efeito protetor do flúor no desenvolvimento da erosão dental

• Ano de defesa: 2014
• Autor(a) principal: Ávila, Daniele Mara da Silva [UNESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Estadual Paulista (Unesp)
• Palavras-chave em Português: Dentes - Erosão; Polímeros; Fluoreto de sódio; Esmalte dentário; Viscosidade; Dental enamel
• Link de acesso: http://hdl.handle.net/11449/127650; http://www.athena.biblioteca.unesp.br/exlibris/bd/cathedra/31-08-2015/000844133.pdf

Dental erosion is a multifactorial process involving tooth demineralization by the chemical action of intrinsic and extrinsic acids. Since the protective effect of fluoride against erosion has been mainly related to fluoride adsorption and calcium fluoride deposits on tooth surface, it was hypothesized that the incorporation of bioadhesive polymers in fluoridated solutions would increase fluoride interaction with the enamel surface, and consequently, enhance its protective effect. In this study, three polymers were tested (Carbopol 980, Carboxymethyl Cellulose and Aristoflex AVC), in pretested concentrations based on the viscosity of the solutions to be used, which simulated a mouthrinse. Bovine enamel specimens were prepared and submitted to a demineralization-remineralization model with immersion in 0.3% citric acid, treatment with polymers solution associated or not to sodium fluoride (900 ppm), and storage in artificial saliva. Initial Knoop hardness (KHN1) and profilometry of all specimens were measured. After the first acid challenge, microhardness were measured again (KHN2), as well as after the first immersion in treatment solutions (KHN3) and after the second acid challenge (KHN4), characterizing the initial erosion analysis. Percentage of remineralization (%rem=KHN3-KHN2/KHN2*100) and of protection (%prot=(KHN4-KHN2/KHN2*100) was determined. The demineralization-remineralization cycling was repeated for five days, 6x/day, with immersion in treatment solutions after the first and last acid immersion of the day. At the end of the experiment, enamel loss was assessed with profilometry, by comparison of the initial and final profiles. Data were analyzed with ANOVA an Tukey's tests (p < 0.05). Regarding rehardening properties, no polymer isolated differed from control. When associated to NaF, Carbopol presented similar %rem compared to NaF control. For initial erosion protection,...