Plasma rico em plaquetas, medula óssea ou quitosana nas osteossínteses minimamente invasivas na tíbia de cães

• Ano de defesa: 2015
• Autor(a) principal: Filgueira, Fabrícia Geovânia Fernandes [UNESP]
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Estadual Paulista (Unesp)
• Palavras-chave em Português: Cão; Ortopedia veterinaria; Ossos - Cirurgia; Fixação interna de fraturas; Consolidação da fratura; Surgery
• Link de acesso: http://hdl.handle.net/11449/128056

Minimally invasive plate osteosynthesis (MIPO) has become widely accepted for the treatment of fractures in small animals, especially because of the preservation of the initial hematoma and minimization of the soft tissues damage. Another way to improve bone healing is the use of biomaterials, such as platelet-rich plasma (PRP), aspirated bone marrow (MO) and chitosan (QUI). The aim of this study was to evaluate the bone healing after the association of MIPO and percutaneous injection of PRP, MO, and QUI in the treatment of tibial fractures in dogs. Clinical and radiographic examination and optical densitometry were used. Thirty dogs from the surgical routine of the Veterinary Teaching Hospital of the Faculty of Agricultural and Veterinarian Sciences (UNESP, Jaboticabal) presenting tibial fractures were used. The groups were formed according to injected biomaterial: group 1 (nothing was injected), group 2 (MO), group 3 (PRP) and group 4 (QUI). Two mililiters of each biomaterial was injected into the fracture site percutaneously just after the surgery. The dogs were evaluated for the intensity of edema formation (EDE), ambulatory activity (DEAM), radiographs and optical densitometry, immediately after surgery and 15, 30, 60, 90 and 120 days postoperatively. There was no significant difference between groups considering EDE and DEAM. Seventy percent of the animals presented member support grade 4 or 5 at 15 days postoperatively. After 30 days, all dogs presented without lameness. Among the groups, there was no statistical difference in the walk, however the group 2 showed the highest percentage (60%) of weight bearing at 15 days. There was a difference considering clinical union in the group 2 (46,87 days). There was no statistical difference in the mineral density of the bone callus formed between the groups and the moments assessed. The PRP, MO and QUI associated with MIPO help bone regeneration in the treatment of tibial fractures in ...