Modulação autonômica cardíaca em pacientes com sequela de tuberculose pulmonar tratada

• Ano de defesa: 2020
• Autor(a) principal: Mendes, Natália Cristina Martins Nunes
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Uberlândia; Brasil; Programa de Pós-graduação em Ciências da Saúde
• Palavras-chave em Português: Sistema nervoso autônomo; Variabilidade da frequência cardíaca; Tuberculose pulmonar; Sequela de tuberculose pulmonar; Modulação autonômica cardíaca; Autonomic nervous system; Heart rate variability; Pulmonary tuberculosis; Cardiac modulation autonomic; Sequelae pulmonary tuberculosis; CNPQ::CIENCIAS DA SAUDE; Cardiotocografia; Tuberculose; Pulmões
• Link de acesso: https://repositorio.ufu.br/handle/123456789/30225; http://doi.org/10.14393/ufu.di.2020.665

To evaluate heart rate variability (HRV) in supine and standing positions in men with sequelae of treated pulmonary tuberculosis (ST) compared to a apparently hea lthy individuals and to correlate lung function with HRV indexes in ST patients. The R-R intervals were captured by a heart rate monitor for 10 minutes in supine and standing position. Subsequently, spirometry was performed. Linear analysis and non-linear analysis HRV were used. For the statistical analysis, we used the Mann-Whitney and t tests to compare the two groups in each posture. Pearson's correlation coefficient and Spearman was used for the relationship between HRV indexes and subgroups ST, absence of obstructive ventilatory disturbance (Without OVD) and mild obstructive ventilatory disorder (Mild OVD). The ST showed postural adaptation in relation to the Control group with greater complexity and less regularity of patterns using the ICN index. The control group had an increase in mixed modulation, with a predominance of LFabs, in both postures, supine and standing. Mild OVD had greater variance (signal variability), greater HF abs and HFnu, and less LFnu in supine and greater HFabs, greater 2UV% and greater ICN in orthostatism. The Without OVD subgroup had a higher LFnu in supine, which was not expected. Cardiac autonomic modulation is compromised in men with ST, but there has been adjustment cardiac autonomic modulation to postural challenge. Mild OVD, this postural adjust had a vagal cardiac predominance and a higher complexity. Even with the absence of a ventilatory disorder in patients with ST, sympathetic cardiac modulation was compromised.