Nível de atividade física e risco de câncer de mama: estudo de caso e controle em usuárias de serviços de saúde pública

• Ano de defesa: 2019
• Autor(a) principal: Bonilha, Elias Campos Martins [UNIFESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Physical Activity Level; Breast Cancer Risk; Case-Control Study; Atividade Motora; Neoplasias Da Mama; Qualidade De Vida
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=8006105; https://repositorio.unifesp.br/handle/11600/60032

Objective: A case-control of outpatient clinic discipline of Mastology (EPM-UNIFESP) study was conducted to examine the association between lifetime physical activity and breast cancer risk. Methods: Sociodemographic, clinical and anthropometric data were collected of the case group (80 women with breast cancer survivors) and of the control group (161 women with benign breast diseases). Two models of physical activity evaluation were applied: “The Lifetime total physical activity questionnaire” (LTPAQ) and the other self-applied questionnaire “Physical activity in the last 12 months” (BAECKE). Descriptive statistics were prepared to characterize the study population and to examine case-control differences. Student t-test and chi-square test were used in addition to multiple logistic regression with (95% CI) evaluated the analysis of the relationship between physical activity and breast cancer, adjusted for age, ethnicity and family history of the disease, which were the significant variables to analyze the relationship between physical activity and breast cancer. Results: The cases and controls had similar sociodemographic, anthropometric and reproductive histories. The differences were higher age, white ethnicity and family history of breast cancer. Both groups were overweight or obesity (body mass index was 28.5 in cases and 28.4 in controls) and had a high waist-hip ratio (0.86 and 0.85, respectively). The exposure of physical activities showed an association with the reduction of the chance of breast cancer (P=0.05 and OR=0.97). The lifetime physical occupational activity evaluated by metabolic equivalent task (MET) conferred a smaller risk of breast cancer for postmenopausal women only (P=0.03 and OR=0.99). Conclusion: An increased cardiovascular risk and overweight were observed in these women. The occupational physical activity reduced breast cancer risk after menopause.