A qualidade de vida na doença do refluxo gastroesofágico: comparação entre os grupos não erosivo e erosivo

• Ano de defesa: 2011
• Autor(a) principal: Maciel, Paulo Roméro [UNIFESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Esophagus; Gastroesophageal reflux; Surveys and questionnaires; Quality of life; Esôfago; Questionário; Refluxo gastroesofágico; Qualidade de vida
• Link de acesso: http://repositorio.unifesp.br/handle/11600/8846

The gastroesophageal reflux disease is one of the most common disorders in medical practice, disease grouping under the same designation, clinical presentations as diverse as the occasional pyrosis, the chronic cough and the refractory asthma, besides the typical symptoms such as the pyrosis, regurgitation, epigastric pain and retrosternal pain. The symptoms are not related with disease severity and affect significantly the quality of people’s life. Objectives: To compare the quality of life in gastroesophageal reflux disease, among the group non-erosive and the erosive one, observing exist in four presentations of the disease: erosive disease without hiatal hernia, erosive disease with hiatal hernia, non-erosive disease with hiatal hernia and non-erosive disease without hiatal hernia. Method: The present study was conducted from a sample of 400 individuals, treated at a clinic specializing in gastroenterology and digestive endoscopy, in the city of Caruaru, in Pernambuco. Were included in the study the patients aged 14 to 82 years old, suffering from gastroesophageal reflux disease. All patients were evaluated clinically, underwent to high digestive endoscopy and to a therapeutic trial with proton pump inhibitors and prokinetics. The questionnaires of quality of life SF-36 and the questionnaire of gastroesophageal reflux symptoms QS-DRGE, both validated for Brazil, evaluated the quality of life. The sample was obtained by inviting the patients already diagnosed and not treated by medication with proton pump inhibitors or prokinetics. Results: The sample of patients with gastroesophageal reflux disease in the statistical tests with the analysis of the questionnaires showed no statistical differences in symptoms and therapeutic results in the four presentations of gastroesophageal reflux disease. Conclusions: The quality of life was similar in patients with and without esophageal lesions, regardless of their nature: erosive disease without hiatal hernia, erosive disease with hiatal hernia, non-erosive disease with hiatal hernia and non-erosive disease without hiatal hernia.