Relação entre os compostos químicos e as categorias psicoativas das plantas psicoativas citadas na obra de Pio Correa: uma ferramenta para a seleção de potenciais bioativos

• Ano de defesa: 2009
• Autor(a) principal: Otsuka, Rafaela Denise [UNIFESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Plantas psicoativas; Pio Correa; Etnofarmacologia; Fitoquímica; Plantas medicinais; Psicotrópicos
• Link de acesso: http://repositorio.unifesp.br/handle/11600/10029

Ethnopharmacological surveys investigate the use of plants and other medicinal and toxic substances by different populations. One of its approaches is researching on the available knowledge of medicinal plants in published literature. The purpose of the current study was read the literary work of Pio Correa and extracts the plants with psychoactive effects. Those plants were classified in: stimulants of Central Nervous System, depressors and disturbants. Current phytochemical studies about these plant species were searched in scientific periodicals and all these information were compiled into a Database, in order to verify the existence or not, of a correlation between chemical compounds present in these plants and their psychoactive categories. From 813 plants extracted from the literary work, 474 belong to stimulants category, 245 to depressors, and 13 to disturbants and there were found phytochemical studies to 77, 31 and 3 (three) of them, respectively. There were observed few variation comparing the chemical compounds presented in the stimulants and depressors categories (phenols, flavonoids, volatiles, carotenoids and steroids), although in different frequencies. However it was observed predominance of some chemical compounds among the plants belonging to uses of each psychoactive category, such as: tonics/fortificants (phenols, flavonóides and volatiles); stimulants/excitants (volatiles, phenols, alkaloids and flavonoids); anxiolytic/hypnotic/sedative (flavonoids and steroids). Among the plants studied, the following families had predominated with their respective chemical compounds: Asteraceae (phenols, flavonoids and volatile compounds), Solanaceae (steroids), Lamiaceae (volatile compounds) and Fabaceae (flavonoids and tannins).These results will facilitate the selection of plant species to be investigated by researchers that focus the psychoactive plants as potentials therapeutics.