Avaliação da condição nutricional, níveis pressóricos e perfil metabólico em crianças com elevado peso ao nascer

• Ano de defesa: 2016
• Autor(a) principal: Ledo, Daniel Lopez [UNIFESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Birth weight; Newborn; Child; Obesity; Blood pressure; Disorders of lipid metabolism; Peso ao nascer; Recém-nascido; Criança; Obesidade; Pressão arterial; Distúrbio do metabolismo dos lipídeos
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=4245469; http://repositorio.unifesp.br/handle/11600/46330

Objective: To identify a possible association between high birth weight (HBW) and overweight / obesity, increased blood pressure levels, altered lipid profile and altered glucose metabolism in children and adolescents between 6 and 12 years of age. Methods: A cross-sectional study with students, enrolled in a public school in the metropolitan region of Sao Paulo. Anthropometric data, family history and blood pressure levels were obtained from 719 children and 518 collected laboratory tests. 25 Risk variables for CVD were waist circumference, blood pressure (SBP/DBP), body mass index (BMI), lipid profile, blood glucose, insulin and insulin resistance (HOMA). The birth weight was classified into 3 groups: low birth weight (LBW < 2,500g), appropriate weight (AW: 2,500g ? BW < 4000g) and high birth weight (HBW ? 4000g). Results: In 719 children evaluated, the average age was 9.5 ± 2.0 years old and 371 (51.6%) were male. There was no statistically significant difference in relation to the classification of nutritional status and birth weight. The average values of Z BMI, waist/height and Z high/age were higher in schoolchildren with HBW, however, without statistically significant difference in relation to the other groups. Children/adolescents with HBW didn?t have a worse lipid or glucose profile and insulin resistance. The group with low birth weight showed the highest percentage of unsuitability for SBP, DBP and triglycerides compared to groups with AW and HBW, even after adjustment for sex. Conclusion: No associations were found between being born with high weight and obesity, blood pressure levels, changes in lipid profile and insulin resistance in children and adolescents.