Avaliações cognitivas e da atenção sustentada na apneia obstrutiva do sono de grau leve

• Ano de defesa: 2016
• Autor(a) principal: Carneiro, Aline de Almeida Millani Gomes [UNIFESP]
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Mild obstructive sleep apnea; Cognition; Neuropsychological tests; PVT; Polysomnography; Apneia obstrutiva do sono leve; Cognição; Testes neuropsicológicos; Polissonografia
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=3724791; http://repositorio.unifesp.br/handle/11600/47299

Introduction: Evidence of related cognitive repercussions in Obstructive Sleep Apnea (OSA) has been well investigated in the literature. However, most of the present studies assess patients with moderate/severe OSA. Objective: Evaluate the effect of mild OSA on the cognitive consequences. Methods: The sample consisted of volunteers of both genders; aged between 18 to 65 years old and body mass index ? 35Kg/m2. We have selected 2 groups; one mild OSA group with Apnea-Hypopnea Index (AHI) from 5 to 15 independently of presenting symptoms/signals, and a control group with AHI < 5; Respiratory Disturb Index (RDI) < 5, Arousal Index (AI) < 15 and Epworth Sleepiness Scale (ESS) < 10. Evaluation between groups was performed by physical exam, full-night polysomnography, battery of cognitive tests, Performance Vigilance Test (PVT). Statistical analysis was performed by descriptive analysis (mean ± standard deviation) and for between groups analysis, univariate General Linear Model (GLM) test and GLM repeated measures, considering significant if p ? 0.05. Results: The sample consisted of 106 individuals, 35 in the control group and 71 in mild OSA group. There were no significant differences in cognitive assessments conducted between mild AOS group and the control group. Conclusion: Patients with mild OSA do not have cognitive impairment compared to control subjects.