Influência do gênero e do índice de massa corpórea na capacidade funcional em pacientes com apneia obstrutiva do sono

Detalhes bibliográficos
Ano de defesa: 2009
Autor(a) principal: Rizzi, Camila Furtado [UNIFESP]
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: http://repositorio.unifesp.br/handle/11600/9755
Resumo: Purpose: To evaluate the functional capacity in men and women with Obstructive Sleep Apnea (OSA) and to analyze its impact on exercise capacity and blood parameters in lean subjects. Methods: OSA patients were selected from database of Sleep Institute of Sao Paulo city. All subjects underwent clinical evaluation, blood sample withdrawal, polysomnography, a maximum limited symptom cardiopulmonary exercise test, 2D-transthoracic echocardiography and spirometry. An Apnea-hypopnea Index (AHI) . 5 events/hour was used for OSA diagnosis. Results: Men had higher peak oxygen consumption (VO2), dioxide of carbon production, oxygen pulse, heart rate (HR) and systolic blood pressure (SBP). A significant negative correlation was found between severity of OSA as measured by AHI, and peak VO2 in women. Exercise performance is similar between lean OSA patients and lean non-OSA subjects considering the peak VO2, anaerobic threshold, and respiratory exchange ratio. High glycemia and cervical circumference enlargement are the main characteristics of lean OSA. There were no differences in HR, SBP and diastolic blood pressure during exercise between women and men with OSA, and between lean subjects. Conclusions: There was a correlation between OSA severity and VO2 in women. OSA did not influence exercise capacity in lean patients. In summary, gender and BMI influences exercise capacity in OSA patients