Valor da difusão (dwi) na quantificação da severidade da pancreatite aguda

• Ano de defesa: 2016
• Autor(a) principal: Tertulino, Franklin de Freitas [UNIFESP]
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: Pancreatite necrosante aguda; Imagem de difusão por ressonância magnética; Diagnóstico diferencial
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=4901420; http://repositorio.unifesp.br/handle/11600/46143

Objective: To test the use of Magnetic Resonance Diffusion Imaging (dRM) To differentiate different levels of severity from acute pancreatitis (AP). Method: Thirty-six patients submitted to dRM and cholangiopancreatography by Magnetic resonance imaging were divided into patients with mild PA (PAL, n = 13),Necrotizing PA (PAN, n = 8), and normal pancreas (PN, n = 15, controls). The pancreas Was divided into head, body and tail, and each segment was classified as According to the characteristics of the images: standard 1, normal; Pattern 2, inflammation Light; And standard 3, necrosis. The apparent diffusion coefficients (apparent Diffusion coefficients, ADCs) were measured in each of the segments and Correlated with clinical diagnoses. Results: 108 segments (three segments per patient) were evaluated. The Segments classified as standard 1 in the PN and PAL groups presented Similar ADC values ??(P = 0.29). The calculated ADC values ??for the Pancreatic segments grouped according to different imaging patterns (1-3) were significantly different (P = 0.001). Comparisons revealed Significant differences in signal strength across all three (P <0.05). Conclusions: dRM was a compatible and safe option to differentiate the In patients with PAL, PAN and PN, especially in patients with With contraindication to contrast MR or computed tomography (which Is traditionally necessary to determine the presence of necrosis). The measurement Of ADCs allowed the precise differentiation between standards 1, 2 and 3.