O efeito da ocitocina intranasal nas funções visuais em criança com transtorno do espectro autista: relato de caso

• Ano de defesa: 2022
• Autor(a) principal: Souto, Sheilla Danielly Dias
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso embargado
• Idioma: por
• Instituição de defesa: Universidade Federal da Paraíba; Brasil; Psicologia; Programa de Pós-Graduação em Neurociência Cognitiva e Comportamento; UFPB
• Palavras-chave em Português: Relato de caso; Função visual; Ocitocina; Autismo; Case report; Visual function; Oxytocin; Autism; CNPQ::CIENCIAS HUMANAS::PSICOLOGIA
• Link de acesso: https://repositorio.ufpb.br/jspui/handle/123456789/26759

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with a high incidence and characterized mainly by deficits in social interaction, communication, and the presence of restrictive and repetitive behavior. The atypical sensory behavior of autistic people has been extensively studied, including the use of oxytocin in the neural symptoms of ASD and the assessment of visual functions, as it is known that visual processing can directly influence the social behavior of these people. The present study aims to report a case of a 13-year-old child diagnosed with ASD who underwent the use of intranasal oxytocin and had eye movement and chromatic and achromatic sensibilities evaluated before and after treatment. Fixations and saccades were measured by eye tracking, color discrimination was analyzed by the Cambridge Color Test and the spatial sensitivity of luminance to contrast was measured before, after 10 minutes of using a dose of 0.2UI/kg of intranasal oxytocin and after its use in staggered doses of 0.2UI/kg and 0.4UI/kg, for three weeks, respectively. The study showed mixed results, as there was no statistically significant reduction in the number of fixations and saccades, but the participant showed greater color discrimination for the Deutan and Tritan confusion axes, reduction of the ellipse and greater sensitivity to contrast after using the dose of 0.2UI/kg of intranasal oxytocin. These results can be attributed to the variation in doses, the duration of the study, the age of the participant and even the type of study described, since the context is fundamental for the success of the therapies. However, this research highlights the importance of understanding the relationship between oxytocin, visual processing, and ASD.