O uso de fotobiomodulação e de Lithothamnium calcareum no tratamento de osteotomia experimental em coelhos (Oryctolagus cuniculus)

• Ano de defesa: 2010
• Autor(a) principal: Natalia Sanchez Ucros
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Minas Gerais; UFMG
• Palavras-chave em Português: coelho; fotobiomodulação; osteotomia; Lithothamnium calcareum; cintilografia óssea; Ortopedia veterinaria; Osteotomia; Coelho Cirurgia
• Link de acesso: http://hdl.handle.net/1843/BUOS-8MUHB7

The purpose of this work was to evaluate LED irradiation in the consolidation of experimental osteotomy in rabbits, by radiographic, bone scintigraphy and histology examinations. Twenty male, New Zealand, white rabbits, 4-5 months of age with an average body mass of 2.5kg, were surgically induced mid-tibial osteotomies, fixed with two intramedullary pins. The animals were randomly divided into two experimental groups (A,B,C,D). The group A received dietcontaining 0.75% of L. calcareum, group B receive the same diet and LED irradiation (50mW of power and 870nm of wave leng), with energy density of 12J/cm2 and continues outflow irradiation for 120 seconds in four points around the osteotomy. Group C received the LED onlyand group D served as a control without further tratement of the osteotomy fixation. LED irradiation was easy to perform to the animals as well as the radiographic evaluations, bouth were performed using only manual restraint. The clinical and laboratory assessments were madeweekly and radiographs and bone scintigraphies were done every 15 days until the end of the experiment. Bone density scans and histology were performed at day 60. Radiographs and bone scintigraphies show consolidation in all cases. A radiographic similarity was observed in theimages between groups A and D and between B and C. The callus development in grups B and C was slightly slower. Histologically there was bone consolidation in all animals of group D (control), none in group B, 75% in group A and 60% in group C. From the results we canconclude that, although there was clinical and radiographic bone consolidation in all cases after 60 days, the control group proved to be better histologically, showing that a healthy organism needs no aid to repair bone. In Group B, the association of LED and L. calcareum showed a slower response. Further research should be conducted to assess the effects of mineral supplementation and photobiomodulation on animals with mineral deficiencies and bone alterations.