Avaliação da composição corporal de mulheres recém-diagnosticadas com câncer de mama

Detalhes bibliográficos
Ano de defesa: 2010
Autor(a) principal: Martins, Karine Anusca lattes
Orientador(a): Freitas Júnior, Ruffo de lattes
Banca de defesa: Não Informado pela instituição
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Goiás
Programa de Pós-Graduação: Programa de Pós Graduação em Ciências da Saúde
Departamento: Faculdade 1::Departamento 1
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tde/2872
Resumo: Introduction: Body composition modification, mainly the increase in total body fat, which is related to a number of illnesses, is an important public health problem, is quite prevalent in breast cancer patents and is directly associated with a negative prognosis for the illness. Objective: To evaluate the body composition, of total body fat and its distribution and lipid profile of women recently diagnosed with breast cancer, at two referral centers in Goiânia, Goiás. Methodology: (Article 1) A cross-sectional, cohort nested study. (Article 2). A case-control study, with 1:1 pairing, carried out in Goiânia, Goiás, Brazil. The data were collected through interviews based on questionnaire, with 62 women, a socio-demographic characterization and an evaluation of body composition using anthropometry including skinfolds (SF) and circumferences, bioelectrical impedance analysis (BIA) and ultrasonography (USG), besides the evaluation of lipid profile. Were carried an data tabulation (Excel/2003) and analysis (SPSS program, version 8.0) and (STATA, Intercooled Stata 8) and were used descriptive statistics. Was used in the data analyses: the Kolmogorov-Smirnov test, ??t?? test, chi-square for tendency, (Mann-Whitney U), Pearson??s chi-square, Fisher??s exact test, and Yates?? correction, odds ratio, Pearson??s correlation coefficient (r), concordance correlation coefficient (CCC) and determination index (r2). The level of significance was: p < 0.05. Results: Compared with the controls, women with breast cancer (cases) had lower stature (1.56m±5.68) and (1.59m±6.92); greater body fat as measured by bioelectrical impedance (BIA) (39.87% ±8.26) and (36.00%±6.85) and (63.98%±6.87); and larger tricipital skinfolds (27.55mm±8.37) and (22.81mm±5.72), respectively. Seventeen (54.84%) cases and 19 (61.29%) controls presented increased abdominal adiposity and 20 (64.52%) of cases and 22 (70.97%) of controls were overweight (BMI ? 25.0 Kg/m2). A moderate concordance (CCC=0.59; r2=0.42; p<0.01) was identified between the methods (BIA and sum of skinfolds - ?SF) for determining body fat (%) and optimal concordance (r2=0.90; CCC=0.91; p<0.01) for body fat (Kg). The comparison between the methods of evaluation body fat distribuition (Waist Circumference (WC) and intra-abdominal thickness (IAT) for (USG) evidenced a moderate concordance (r2=0.49; p<0.01), between the methods. No association was found between the lipid profile and breast cancer occurrence. Conclusions: Women with breast cancer presented lower stature, a greater percentage of body fat and and larger tricipital skinfolds than women without cancer. A moderate concordance, between the methods used in determining total body fat (%) and a optimal concordance in determining body fat (Kg) were found. A moderate concordance were found between the methods in determining body fat distribution (IAT x WC).