Detalhes bibliográficos
Ano de defesa: |
2009 |
Autor(a) principal: |
RUIZ JÚNIOR, Everaldo
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Orientador(a): |
COSTA, Paulo Sérgio Sucasas da
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Banca de defesa: |
Não Informado pela instituição |
Tipo de documento: |
Dissertação
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Tipo de acesso: |
Acesso aberto |
Idioma: |
por |
Instituição de defesa: |
Universidade Federal de Goiás
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Programa de Pós-Graduação: |
Mestrado em Ciências da Saúde
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Departamento: |
Ciências da Saúde - Medicina
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País: |
BR
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Palavras-chave em Português: |
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Palavras-chave em Inglês: |
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Área do conhecimento CNPq: |
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Link de acesso: |
http://repositorio.bc.ufg.br/tede/handle/tde/1765
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Resumo: |
Hemoglobinopathies are the most common inherited disorders in humans; the most frequent are hemoglobins S and C. This study evaluates the prevalence of hemoglobin patterns at the city of Goiânia, state of Goiás, Brazil, using neonatal screennig. Prevalence was compared between exams from the public and private systems. Blood samples from 90,127 newborns were obtained. Hemoglobinopathies were identified in a total of 61 (7:10.000) newborns. The prevalence in public and private systems was 7 and 3 per 10,000 respectively (p=0.081). In 3,243 (371:10,000) hemoglobinopathy traits were detected. The public system´s prevalence was 400:10,000 and in the private system it was 177:10,000 (p=0.0001). The prevalence of sickle cell disease was 4.3:10,000 live birth overall; in the public system, it was 5:10,000 and in the private system it was 2:10,000 (p=0.133). We can conclude that sickle disease is of high prevalence in children at public and private systems. The neonatal screening information is of paramount importance for early diagnosis of sickle disease and people with sickle traits |