Avaliação cognitiva de pacientes com glaucoma e sua comparação com indivíduos com demência de Alzheimer

Detalhes bibliográficos
Ano de defesa: 2014
Autor(a) principal: Maurano, Stephanie Toledo Piza lattes
Orientador(a): Silva, Leopoldo Magacho dos Santos lattes
Banca de defesa: Silva, Leopoldo Magacho dos Santos, Isaac, David Leonardo Cruvinel, Lima, Francisco Eduardo Lopes de, Ferreira, Sandra de Fátima Barbosa, Carneiro, Haroldo Maciel
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Goiás
Programa de Pós-Graduação: Programa de Pós-graduação em Ciências da Saúde (FM)
Departamento: Faculdade de Medicina - FM (RG)
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tede/5652
Resumo: This study aimed to evaluate the cognitive performance of patients with glaucoma and compare it to people with Alzheimer's disease (AD). Glaucoma patients, AD and control group (healthy elderly) were assessed using the MMSE (Mini Mental State Examination) and the subtests verbal fluency, word list memory, delayed recall of the word list, word list recognition test Boston naming test and construction praxis from CERAD (Consortium to Establish a Registry for Alzheimer's Disease). The results of each test were compared between the groups. One hundred and twelve patients were evaluated, 50 healthy elderly with a mean age of 71.2 ± 5.2 years; 41 patients with glaucoma (72.2 ± 4.4 years) and 21 patients with AD (79.0 ± 7.6 years). AD patients had, on average, advanced disease. Noted a reduction in the cognitive assessment tests in all evaluated, both for patients with glaucoma, and for those with AD compared with controls (p <0.001 for all). When the results from patients with glaucoma and AD were paired, it was noted that the AD patients had lower cognitive function (p <0.001), except for the tests CERAD Boston (p = 0.1) and praxis (p = 0.6). Glaucoma patients, however, presented results of cognitive tests similar to those described for patients with mild AD, including lower values for MMSE (21.9 ± 3.7), Boston (10.6 ± 2.6) and praxis (5.9 ± 2.3).