Fatores de risco associados à ocorrência de anticorpos anti-Neospora caninum em fêmeas bovinas leiteiras da microrregião leste do estado de Antioquia - Colômbia

• Ano de defesa: 2015
• Autor(a) principal: Llano, Horwald Alexander Bedoya
• Orientador(a): Silva, Andréa Caetano da
• Banca de defesa: Silva, Andréa Caetano da, Silva, Márcia Benedita de Oliveira, Oliveira, Vanessa Silvestre Ferreira de
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Goiás
• Programa de Pós-Graduação: Programa de Pós-graduação em Ciência Animal (EVZ)
• Departamento: Escola de Veterinária e Zootecnia - EVZ (RG)
• País: Brasil
• Palavras-chave em Português: Bovinos leiteiros; Colômbia; Epidemiologia; Neosporose; Regressão logística; Sorologia
• Palavras-chave em Inglês: Dairy cattle; Colombia; Epidemiology; Logistic regression; Neosporosis; Serology
• Área do conhecimento CNPq: MEDICINA VETERINARIA::PATOLOGIA ANIMAL; TECNOLOGIA DE ALIMENTOS::TECNOLOGIA DE PRODUTOS DE ORIGEM ANIMAL
• Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tede/5560

Bovine neosporosis is a parasitic disease distributed worldwide, that causes large economic losses due to abortions, low milk production, neonatal mortality and repeated estrus. Because of the limited information from Colombia’s studies, we aimed to identify the risk factors associated with this infection and to determine its seroprevalence for Antioquia's east region, which is the largest milk producer state of the country. We collected 1,038 blood samples from Holstein, Jersey and crossbred cows from 31 farms in five municipal districts. An epidemiologic questionnaire was applied to the owner of each farm. For the determination of seropositivity we employed indirect ELISA and for titration of positive samples we used the indirect immunofluorescence assay test (cutoff ≥ 1:200). The soropositivity for N. caninum was estimated to be 28.32% (294/1038). All properties had at least one positive animal with frequencies of seropositivity ranging from 5.5% to 50%. Analysis of risk factors was performed by Chi-square test (X²) and multiple logistic regression. The presence of dogs, history of abortion, breed, age, replacement cattle purchase outside the farm, gestation, repetition of estrus, type of milking and the presence of chickens on farms showed significant association with seropositive animals by Chi-square test (X²=P<0.25) and were selected for a final multivariable logistic regression model where the history of abortion (OR = 5.33, p <0.001), age (OR = 1.7, p = 0.038), replacement cattle purchase outside the farm (OR = 1.54 p = 0.008) and manual milking (OR = 1.69, p = 0.0029) were identified as risk factors. These findings record the first report of seroprevalence and risk factors for the region and allow us to conclude that N. caninum is widely distributed in the evaluated properties and significantly associated with these factors.