Qualidade de vida e morbidade tardia após a biópsia do linfonodo sentinela ou linfadenectomia axilar em mulheres submetidas ao tratamento do câncer de mama

• Ano de defesa: 2014
• Autor(a) principal: Morais, Fernanda Dorneles de
• Orientador(a): Freitas Júnior, Ruffo de
• Banca de defesa: Freitas Júnior, Ruffo de , Mota, Dálete Delalibera Corrêa, Bergmann, Anke, Corrêia, Rosangela da Silveira, Paulinelli, Régis Resende
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Goiás
• Programa de Pós-Graduação: Programa de Pós-graduação em Ciências da Saúde (FM)
• Departamento: Faculdade de Medicina - FM (RG)
• País: Brasil
• Palavras-chave em Português: Câncer de mama; Qualidade de vida; Morbidade; Linfadenectomia axilar; Biópsia do linfonodo sentinela
• Palavras-chave em Inglês: Breast cancer; Quality of life; Morbidity; Sentinel lymph node biopsy; Axillary lymphadenectomy
• Área do conhecimento CNPq: CIENCIAS DA SAUDE::MEDICINA
• Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tede/6442

The aim of this study was to evaluate quality of life (QoL) and late morbidity after axillary lymphadenectomy (AL) or sentinel lymph node biopsy (SLNB) in breast cancer survivors. :This was an analytical, cross-sectional study with 100 participants. Sociodemographic and clinical data were obtained at interviews, from patients’ medical charts and by applying the EORTC QLQ-C30 and QLQ-BR23 questionnaires. In addition, a kinetic analysis was made of the patients’ upper limb function to investigate the presence of possible late morbidities (pain, limited range of motion [ROM], sensory disturbance and lymphedema). Results: The patients who underwent AL worse QoL than those submitted to SLNB in 10 domains. Following AL, there was a greater likelihood of the patient developing: lymphedema (odds ratio [OR]: 17.22; 95% confidence interval [95%CI]: 2.15-137.57), reduced flexion (OR: 6; 95%CI: 2.45-14.68), reduced abduction (OR: 5.67; 95%CI: 2.14–15.00), sensory disturbance (OR: 4.03; 95%CI: 1.71–9.49) and pain (OR: 1.74; 95%CI: 1.16–2.61). Conclusions: These results confirm the benefit of SLNB due to its lower arm morbidity impact on QoL, compared with AL. All morbidities were more common and more likely to occur in the patients submitted the dissection axillary. In addition, the high frequency of limitations in movement and pain in both groups merits particular attention.