Avaliação histopatológica do tecido pericoronário de dentes não irrompidos com imagem radiográfica de normalidade
| Ano de defesa: | 2007 |
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| Autor(a) principal: | |
| Orientador(a): | |
| Banca de defesa: | |
| Tipo de documento: | Dissertação |
| Tipo de acesso: | Acesso aberto |
| Idioma: | por |
| Instituição de defesa: |
Programa de Pós-graduação em Patologia
Patologia |
| Programa de Pós-Graduação: |
Não Informado pela instituição
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| Departamento: |
Não Informado pela instituição
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| País: |
Não Informado pela instituição
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| Palavras-chave em Português: | |
| Link de acesso: | https://app.uff.br/riuff/handle/1/17566 |
Resumo: | The teeth, at the end of the eruptive process, undertake their position in the mouth in an expected period of time. When this dos not occur, these teeth are called unerupted teeth. The unerupted teeth more frequently found are the third molars. The removal of such teeth is a very common surgery procedure and it has therapeutic indications universally accepted, such as its association to odontogenics cysts and tumors, the presence of dental caries non-restorable, radicular reabsorption, and bone destruction. The cystic or neoplasic alterations associated with unerupted teeth are related to the structures present in the dental follicle, pathological modifications of the reduced epithelium enamel and remnants from the dental slide. The therapeutic conducts only through radiographic image, and do not be send the secluded material to histopathologic analysis, may result in an unfamiliarity with the presence of pathological alterations in the pericoronary tissue when the radiographic image reveals itself compatible to normality. The morphological differentiation between the dental follicle and an incipient pathological alteration is determinant to diagnosis and further treatment with patient attendance. This objective of this work was to evaluate the occurrence of alterations in pericoronal tissues of unerupted teeth with radiographic image of normality, established by panoramic radiography, through the histopathologic analysis and a immunohistochemical study using CK19 e Ki-67. We analyzed 63 pericoronal tissues from a total of 36 patients, resulting in 43 (68,3%) teeth were removed from females, and 20 (31,7%) from male. The patients age varied from 12 and 32 years old, and the age average was 20,5 years old. Fifteen (23,8%) pericoronal tissues were associated with the 3DMS, 12 (19%) with the 3EMS, 16 (25,4%) with the 3EMI, 18 (28,6%) with the 3DMI, 1 (1,6%) with a supranumerary tooth from INCS region, and 1 (1,6%) supranumerary from PMIs region. Considering the pericoronary radiological size, 22 (34,9%) pericoronal tissues were presented with up to 1mm in thickness, 29 (46%) with up to 2mm, and 12 (19%) with up to 3mm. Stratified squamous epithelium was identified in 18 (28,6%) pericoronal tissues and the reduced enamel epithelium was found in 43 (68,3%) of them. Chronic inflammation was identified in 24 (38,1%) samples, being the focal moderate inflammation the most frequent. Odontogenic epithelium remnants were discovered in 61 (96,8%) and dystrophic calcifications in 39 (61,9%) pericoronal tissues. As for the pericoronal tissues diagnosis, 52 (82,5%) were identified as pericoronary follicle, 10 (15,9%) as dentigerous cysts, and 1 (1,6%) keratocistic odontogenic tumor. In relation to the antibody Ki-67, its demarcation was basal and supra-basal in 9 (17,3%) pericoronary follicle, in all dentigerous cysts, as well as in the keratocistic odontogenic tumor. The antibody CK 19 was positive in 49 (98%) pericoronary follicle, in the 10 (100%) dentigerous cysts, and in the keratocistic odontogenic tumor. The presence of histopathologic alterations is frequent (inflammation, squamous metaplasia, and cystic transformation) in pericoronal tissues of unerupted teeth with radiographic image of normality. It is necessary that all clinic, radiographic, and transoperatory information are sent together with pericoronal tissues and removed teeth to histopathologic analysis in order to help the final diagnosis |