Associação entre conteúdo de água corporal em idosos e alterações funcionais da junção esofagogástrica avaliadas por manometria esofágica de alta resolução

• Ano de defesa: 2018
• Autor(a) principal: Silva, Vicente Conrado
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Palavras-chave em Português: Sarcopenia; Composição Corporal; Envelhecimento; Manometria; Diafragma
• Link de acesso: http://www.repositorio.ufc.br/handle/riufc/39470

Sarcopenia is a process closely linked to aging and losing mass, performance and muscle function. The diaphragm is a striated muscle and its crural portion is an important component of the esophagogastric junction (EGJ). Based on these assumptions, this study aimed to verify the association between the body solution and a motor function of JEG in elderly people. This is a transversal and descriptive study of a quantitative approach, performed on elderly human from the Geriatrics Outpatient Clinic of the Walter Cantídio University Hospital. The sample, composed of 17 volunteers, was submitted to a clinical evaluation for the assessment of typical and atypical symptoms of Gastroesophageal Reflux Disease, physical examination for the collection of anthropometric measurements, evaluation of body composition by dilution of deuterium in saliva, evaluation of motility esophageal evaluation of EGJ by high-resolution esophageal manometry (HRM), maximal inspiratory pressure (MIP) measurement by manovacuometry, in addition to ambulatory 24-h impedance-pH measurements. The research protocol was approved by the Research Ethics Committee of the Federal University of Ceará (UFC) and the patients signed the Free and Informed Consent Term. After analyzing the body composition, the participants were divided into two groups: Lower % of body water (n = 9) and Higher % of body water (n = 8). The groups were similar in age and gender. There was no difference in the scores of the symptom questionnaires, nor for esophageal motility variables. The variables EGJ axial displacement (DS), contractile integral (CI), Maximum JEG Pressure (MPÁX), EGJ Contractility Index (CI-EGJ) and Total EGJ Activity (AT-JEG) were statistically different between groups. Thus, despite some limitations like the size and type of the sample, this study may conclude that the elderly people with low muscle mass present alterations in the motor function of the EGJ. Keywords: Sarcopenia. Body composition. Aging. Manometry. Crural Diaphragm