O uso de dexametasona e etoricoxibe para a prevenção e controle da dor pós-operatória após cirurgia periodontal

Detalhes bibliográficos
Ano de defesa: 2009
Autor(a) principal: Steffens, João Paulo lattes
Orientador(a): Pilatti, Gibson Luiz lattes
Banca de defesa: Santos, Fábio André dos lattes, Deliberador, Tatiana Miranda lattes
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: UNIVERSIDADE ESTADUAL DE PONTA GROSSA
Programa de Pós-Graduação: Programa de Pós-Graduação em Odontologia
Departamento: Clinica Integrada, Dentística Restauradora e Periodontia
País: BR
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://tede2.uepg.br/jspui/handle/prefix/1756
Resumo: Several anti-inflammatory drugs have been used to reduce pain and discomfort after periodontal surgeries. The purpose of this study was to evaluate the efficacy of etoricoxib and dexamethasone on pain prevention after open flap debridement surgery. For this prospective, double-masked, cross-over, placebo-controlled randomized clinical trial, open flap debridement surgeries were performed on 15 patients who presented chronic periodontitis after nonsurgical periodontal therapy at three sextants. Each patient was submitted to three surgical procedures with intervals of 30 days and received one of the premedication protocols one hour before surgery: G1- placebo; G2- 8 mg dexamethasone; G3- 90 mg etoricoxib. Pain intensity and discomfort were evaluated by visual analog scale (VAS), 101-point numerical rate scale (NRS-101) and a 4-point verbal rate scale (VRS-4) during 8 hours after surgery and three times a day on the 3 following days. Data were submitted to appropriate statistical analysis. The results demonstrated that G2 and G3 presented reduced postoperative pain intensity levels than G1. There were statistically significant differences at 4, 5, 6, 7 and 8 hour-period after surgery (Friedman test; p<0.05). Besides, rescue medication intake was significantly lower for G2 and G3 than for G1 (p<0.05). It was concluded that the adoption of a preemptive medication protocol using etoricoxib or dexamethasone may be considered effective on pain prevention after open flap debridement surgeries.