Nefropatia induzida por contraste após tomografia computadorizada

• Ano de defesa: 2009
• Autor(a) principal: Selistre, Luciano da Silva
• Orientador(a): Saitovitch, David
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Pontifícia Universidade Católica do Rio Grande do Sul; Porto Alegre
• Palavras-chave em Português: MEDICINA; CLÍNICA MÉDICA; NEFROLOGIA; NEFROPATIAS; INSUFICIÊNCIA RENAL; MEIOS DE CONTRASTE; TOMOGRAFIA COMPUTADORIZADA
• Link de acesso: http://hdl.handle.net/10923/4427

Contrast-induced nephropathy (CIN) is defined as worsening in renal function after administration of parenteral contrast and exclusiona of other causes. CIN is usually manifested as acute non-oliguric renal failures. Cases of CIN are usually defined by a fixed (0. 5 mg/dl) or proportionate (25%) rise in serum creatinine levels 24-48 hours after exposure to the contrast medium. Prevention strategies are based on the correction of factors leading to the development of CIN and are divided into choice of less nephrotoxic contrast (non-ionic); improvement in the patient’s clinical status through hydration; use of drugs that reduce renal vasoconstriction and oxidative stress; and temporary suspension of drugs with nephrotoxic potential or that are hamful in case of reduced glomerular filtration. This review aims on the management recommendations to prevent its occurrence.