Prevalência de síndrome metabólica em idosos atendidos em um ambulatório de clínica médica de hospital universitário do sul do Brasil e associação com declínio cognitivo

• Ano de defesa: 2011
• Autor(a) principal: Pereira, Adriane Miró Vianna Benke
• Orientador(a): Schwanke, Carla Helena Augustin
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Pontifícia Universidade Católica do Rio Grande do Sul; Porto Alegre
• Palavras-chave em Português: MEDICINA; GERIATRIA; GERONTOLOGIA; IDOSOS; ENVELHECIMENTO; EPIDEMIOLOGIA; SÍNDROME METABÓLICA; COGNIÇÃO; AMBULATÓRIO HOSPITALAR
• Link de acesso: http://hdl.handle.net/10923/3589

Introduction: Metabolic Syndrome (MetS) is a complex disorder associated with increased occurrence of cardiovascular disease and diabetes. Recently, its association with the cognitive decline (CD) in the elderly has been described. Objectives: To determine the prevalence of MetS and CD in elderly patients treated at the Internal Medicine’s Clinic 37 of the Clinics Hospital of the Federal University of Paraná, and verify if there is an association of MetS and its individual components with CD. Methods: observational, transversal, descriptive-analytical study that investigated sample of 133 elderly patients (60 years and over) treated at the Internal Medicine’s Clinic 37 of the Clinics Hospital of the Federal University of Paraná within the period from March 1st 2010 to October 30th 2010. The criterion established by the National Cholesterol Education Program Adult Treatment Panel III (NCEP- ATPIII) was used for the characterization of MetS. The tracking of the CD was performed through the Mini Mental State Examination, and the cultural, socio-demographic and health-related information were obtained through the application of a general questionnaire specific for the research. The data collected were stored in a database developed for the Project in Access 2007. The data analysis, performed with the statistical software SPSS version 17. 0, implicated descriptive procedures; Chi-square Test for the univariate analyses; Pearson’s Chi-square Test, Continuity Correction, Fisher’s Exact Probability Test, Monte Carlo Method and Student’s t-test for the bivariate analyses. Binary Logistic Regression and Odds Ratio were used for the multivariate analysis. Results: The average age of the participants was 68. 7 ±5,8 years old, mostly woman, 66,9% (n=89). The predominance was of white elderly people 81. 2% (n=108), with schooling between 1 and 4 years, 60. 9% (n=81) and family income of up to two Brazil’s minimum wage, 51. 4% (n=58). The prevalence of MetS in the general sampling was of 63. 9% (n=89), being 71. 8% among the women and 28. 2% among the men. CD was present in 21. 1% of the participants, and high glycemic index or hyperglycemia in treatment and lack of physical activity were identified as predictors of cognitive decline. The MetS was positively associated with CD, and the group with MetS had 5. 1 times greater risk of developing CD than the group without MetS, where the influence of control variables on physical activities, triglycerides, sex and fasting glucose was held constant. Conclusion: The prevalences of MetS and CD were high in this sampling. According to the results obtained in the present study, we found that physical inactivity and abnormal blood glucose levels or DM treatment were predictive factors for cognitive decline.