Relação entre comorbidades e declínio cognitivo leve em pacientes clínicos com idade maior que 50 anos na cidade de Sanatana do Livramento, RS

• Ano de defesa: 2011
• Autor(a) principal: Silva, João Augusto de Vasconcelos da
• Orientador(a): De Carli, Geraldo Attilio
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Pontifícia Universidade Católica do Rio Grande do Sul; Porto Alegre
• Palavras-chave em Português: MEDICINA; GERIATRIA; GERONTOLOGIA; IDOSOS; ENVELHECIMENTO; COMORBIDADE; COGNIÇÃO; MANIFESTAÇÕES NEUROCOMPORTAMENTAIS
• Link de acesso: http://hdl.handle.net/10923/3669

Population aging is a worldwide phenomenon with direct consequences on public health systems. One of the main consequences of the growth of this segment is the increasing prevalence of dementia. The objective of this study is to determine the prevalence of Mild Cognitive Impairment (MCI) in patients 50 years or older and its relation to co morbidities. It is a prospective cross-sectional study of patients of a outpatient clinic in the city of Santana do Livramento, between the months of July and December 2010. The Mini-Mental State Examination (MMSE) was administered (12 points for the illiterate, 17 points for patients with 1-8 years of study incomplete and 25 points for patients with ≥ 8 years of schooling) as well as the Rey Recall Test (with standard deviation less than -2. 0 points) as the main screening tests for clinical diagnosis of MCI. The Geriatric Depression Scale 15 (GDS15), the Kartz Index, the Activities of Daily Living (ADLs) and the Montreal Cognitive Assessment (MoCA) were used as secondary tests for the clinical diagnosis, the last one being used as an experimental cognitive test for the Brazilian population. The results showed that the prevalence of clinical diagnosis of MCI was 11. 9%. The age and average education years was 64. 8 ± 9. 3 and 6. 2 ± 3. 6, respectively. In relation to co morbidities, the polypharmacy, diabetes mellitus and low HDL-c were significantly associated with MCI (p = 0. 034, p=0. 050, p = 0. 033, respectively). The MMSE showed a stronger association (p= <0. 001) with attention and math calculation, memory recall and language. The MoCA test was found to be significant for the diagnosis and only the subitems memory recall and visual-spatial data showed statistically significant data (p = <0. 001).In conclusion, the evaluation of the clinical diagnosis of MCI comprises several steps and requires a multidisciplinary look . The prevalence of MCI in outpatients is consistent with that expected for their age. Among the co morbidities, diabetes mellitus, low HDL-C and polypharmacy were significantly associated with MCI.