Detalhes bibliográficos
Ano de defesa: |
2010 |
Autor(a) principal: |
Coutinho, Geraldo Gaspar Paes Leme
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Orientador(a): |
Cury, Patricia Maluf
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Banca de defesa: |
Lopes, José Carlos
,
Naum, Paulo César
,
Angulo, Ivan de Lucena
,
Godoy, José Maria Pereira de |
Tipo de documento: |
Tese
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Tipo de acesso: |
Acesso aberto |
Idioma: |
por |
Instituição de defesa: |
Faculdade de Medicina de São José do Rio Preto
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Programa de Pós-Graduação: |
Programa de Pós-Graduação em Ciências da Saúde::123123123123::600
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Departamento: |
Medicina Interna; Medicina e Ciências Correlatas::123123123123::600
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País: |
BR
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Palavras-chave em Português: |
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Palavras-chave em Inglês: |
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Palavras-chave em Espanhol: |
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Área do conhecimento CNPq: |
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Link de acesso: |
http://bdtd.famerp.br/handle/tede/66
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Resumo: |
To evaluate the efficacy of iron supplements given at intervals corresponding to the mean life of red blood cells compared to weekly supplementation, in reducing the prevalence of preschool anemia. Method: Ninety-nine children from public day care centers with ages from 24 to 59 months old were randomly divided into two groups. This is a randomized comparative study. All the children received 40 doses of 30 mg of ferrous sulfate during a 10-month intervention period. Group 1 received once weekly supplementation and Group 2 received supplementation in two 5-month cycles, each cycle consisting of one month of supplementation (20 workdays) and four months without supplementation. Results: The prevalence of anemia after the supplementation regimens reduced from 20.20% to 5.05% (p < 0.0005); the reduction was not significantly different between the two groups (p = 0.35). The mean hemoglobin concentration increased in both groups (Group 1: 0.27 g/dL; p < 0.016 and Group 2: 0.47 g/dL; p < 0.0005) without significant differences between the groups (p = 0.17). Conclusions: The two regimens reduced the prevalence of anemia, were low-cost, and with high rate of compliance. The regimen in cycles was evaluated easier to apply than the weekly one. |