Eficácia do procedimento de suplementação com ferro em ciclos para redução da anemia em pré-escolares

Detalhes bibliográficos
Ano de defesa: 2010
Autor(a) principal: Coutinho, Geraldo Gaspar Paes Leme lattes
Orientador(a): Cury, Patricia Maluf lattes
Banca de defesa: Lopes, José Carlos lattes, Naum, Paulo César lattes, Angulo, Ivan de Lucena lattes, Godoy, José Maria Pereira de
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Faculdade de Medicina de São José do Rio Preto
Programa de Pós-Graduação: Programa de Pós-Graduação em Ciências da Saúde::123123123123::600
Departamento: Medicina Interna; Medicina e Ciências Correlatas::123123123123::600
País: BR
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Área do conhecimento CNPq:
Link de acesso: http://bdtd.famerp.br/handle/tede/66
Resumo: To evaluate the efficacy of iron supplements given at intervals corresponding to the mean life of red blood cells compared to weekly supplementation, in reducing the prevalence of preschool anemia. Method: Ninety-nine children from public day care centers with ages from 24 to 59 months old were randomly divided into two groups. This is a randomized comparative study. All the children received 40 doses of 30 mg of ferrous sulfate during a 10-month intervention period. Group 1 received once weekly supplementation and Group 2 received supplementation in two 5-month cycles, each cycle consisting of one month of supplementation (20 workdays) and four months without supplementation. Results: The prevalence of anemia after the supplementation regimens reduced from 20.20% to 5.05% (p < 0.0005); the reduction was not significantly different between the two groups (p = 0.35). The mean hemoglobin concentration increased in both groups (Group 1: 0.27 g/dL; p < 0.016 and Group 2: 0.47 g/dL; p < 0.0005) without significant differences between the groups (p = 0.17). Conclusions: The two regimens reduced the prevalence of anemia, were low-cost, and with high rate of compliance. The regimen in cycles was evaluated easier to apply than the weekly one.