Análise da evolução da multirressistência de bactérias gram negativas no Hospital de Base de São José do Rio Preto no Período de 1999 a 2008

• Ano de defesa: 2011
• Autor(a) principal: Oliveira, Viviane Decicera Colombo
• Orientador(a): Rubio, Fernando Góngora
• Banca de defesa: Conterno, Lucieni de Oliveira , Cabrera, Eliana Márcia Sotello
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Faculdade de Medicina de São José do Rio Preto
• Programa de Pós-Graduação: Programa de Pós-Graduação em Ciências da Saúde
• Departamento: Medicina Interna; Medicina e Ciências Correlatas
• País: BR
• Palavras-chave em Português: Bactéria Gram Negativa; Multidroga-resistente; Evolução; Hospital Terciário
• Palavras-chave em Inglês: Gram Negative Bacteria; Multidrug-Resistance; Trends; Tertiary Hospital
• Área do conhecimento CNPq: CNPQ::CIENCIAS DA SAUDE::MEDICINA::CLINICA MEDICA::DOENCAS INFECCIOSAS E PARASITARIAS
• Link de acesso: http://bdtd.famerp.br/handle/tede/96

Hospital bacterial resistance to multiple antibiotics is a great concern worldwide. This study objective was to know the multidrug-resistantance (MDR) agents, clinical materials, origin, trends, and to correlate them with the bacterial sensitivity and antimicrobial consumption. A total of 53,316 nosocomial bacteria were assessed in a tertiary hospital during the period from 1999 to 2008. MDR was defined for gram negative bacteria (GNB) when it presented resistance to two or more classes/groups of antibiotics. GNB were predominant (66.1%). GNB MDR had a global increase of 3.7 times in the end of the period. Acinetobacter baumannii was the most prevalent (36.2%). The most frequent materials were urinary and respiratory. A significant increase occurred during the period of 4.8 and 14.6 times of the A. baumannii and K. pneumoniae, respectively. Sixty-seven percent of GNB MDR was from the Intensive Care Units. A. baumannii resistance to carbapenemics increased from 7.4% to 57.5% during the period, concomitant to the consumption increase. The resistance of K. pneumoniae to the cephalosporins had a high increase during the decade. P. aeruginosa decreased in these last two years with a recovery of the sensitivity.