Model-based control of enzyme yield in solid-state fermentation

• Main Author: Bück, A.
• Publication Date: 2015
• Other Authors: Casciatori, F. P. [UNESP], Thoméo, J. C. [UNESP], Tsotsas, E.
• Format: Conference object
• Language: eng
• Source: Repositório Institucional da UNESP
• Download full: http://dx.doi.org/10.1016/j.proeng.2015.01.163; http://hdl.handle.net/11449/168214
• topic: distributed parameter system; drying; feedback control; heat and mass transfer; solid-state fermentation

Solid-state fermentation is gaining increasing importance for the production of high-added value products, for instance enzymes, from agro-industrial by-products. The main difficulty in operating this process in packed-bed bioreactors is the development of temperature and moisture gradients along the reactor length which decrease the overall productivity. In this work a practically relevant feedback control scheme is developed that allows influencing and equalizing the moisture and temperature distributions along the packed-bed bioreactor during solid-state fermentation. This prevents locally critical process conditions which may necessitate the shutdown of the operation of the bioreactor.