Propylthiouracil Induced Pulmonary-Renal Syndrome: a Case Report.

Bibliographic Details
Main Author: Boattini, M
Publication Date: 2015
Other Authors: Rodrigues, A, Nascimento, P, Luz, KC, Castelo Branco, S, Rodrigues, N, Cachado, P, Garcia, T
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.17/2315
Summary: Propylthiouracil (PTU) is known to induce antineutrophil cytoplasmatic antibody (ANCA) seropositivity; however, small vessel vasculitis (SVV) with pulmonary and renal involvement is rare. We present the case of an 81-year-old woman on PTU treatment due to toxic nodular goitre who developed alveolar hemorrhage and rapidly progressive glomerulonephritis. The authors highlight the importance of early recognising drug-induced pulmonary-renal syndrome (PRS) in order to avoid unnecessary tests, a delay in the diagnosis and evolution to end-stage kidney disease or life-threatening conditions.
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spelling Propylthiouracil Induced Pulmonary-Renal Syndrome: a Case Report.HSM MEDHCC NEFGlomerulonephritis/chemically inducedHemorrhage/chemically inducedLung Diseases/chemically inducedPropylthiouracil/adverse effectsAged, 80 and overPropylthiouracil (PTU) is known to induce antineutrophil cytoplasmatic antibody (ANCA) seropositivity; however, small vessel vasculitis (SVV) with pulmonary and renal involvement is rare. We present the case of an 81-year-old woman on PTU treatment due to toxic nodular goitre who developed alveolar hemorrhage and rapidly progressive glomerulonephritis. The authors highlight the importance of early recognising drug-induced pulmonary-renal syndrome (PRS) in order to avoid unnecessary tests, a delay in the diagnosis and evolution to end-stage kidney disease or life-threatening conditions.Sociedade Portuguesa de ReumatologiaRepositório da Unidade Local de Saúde São JoséBoattini, MRodrigues, ANascimento, PLuz, KCCastelo Branco, SRodrigues, NCachado, PGarcia, T2015-10-22T12:16:02Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/2315enginfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-06T16:48:55Zoai:repositorio.chlc.pt:10400.17/2315Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T00:20:05.187400Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Propylthiouracil Induced Pulmonary-Renal Syndrome: a Case Report.
title Propylthiouracil Induced Pulmonary-Renal Syndrome: a Case Report.
spellingShingle Propylthiouracil Induced Pulmonary-Renal Syndrome: a Case Report.
Boattini, M
HSM MED
HCC NEF
Glomerulonephritis/chemically induced
Hemorrhage/chemically induced
Lung Diseases/chemically induced
Propylthiouracil/adverse effects
Aged, 80 and over
title_short Propylthiouracil Induced Pulmonary-Renal Syndrome: a Case Report.
title_full Propylthiouracil Induced Pulmonary-Renal Syndrome: a Case Report.
title_fullStr Propylthiouracil Induced Pulmonary-Renal Syndrome: a Case Report.
title_full_unstemmed Propylthiouracil Induced Pulmonary-Renal Syndrome: a Case Report.
title_sort Propylthiouracil Induced Pulmonary-Renal Syndrome: a Case Report.
author Boattini, M
author_facet Boattini, M
Rodrigues, A
Nascimento, P
Luz, KC
Castelo Branco, S
Rodrigues, N
Cachado, P
Garcia, T
author_role author
author2 Rodrigues, A
Nascimento, P
Luz, KC
Castelo Branco, S
Rodrigues, N
Cachado, P
Garcia, T
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Unidade Local de Saúde São José
dc.contributor.author.fl_str_mv Boattini, M
Rodrigues, A
Nascimento, P
Luz, KC
Castelo Branco, S
Rodrigues, N
Cachado, P
Garcia, T
dc.subject.por.fl_str_mv HSM MED
HCC NEF
Glomerulonephritis/chemically induced
Hemorrhage/chemically induced
Lung Diseases/chemically induced
Propylthiouracil/adverse effects
Aged, 80 and over
topic HSM MED
HCC NEF
Glomerulonephritis/chemically induced
Hemorrhage/chemically induced
Lung Diseases/chemically induced
Propylthiouracil/adverse effects
Aged, 80 and over
description Propylthiouracil (PTU) is known to induce antineutrophil cytoplasmatic antibody (ANCA) seropositivity; however, small vessel vasculitis (SVV) with pulmonary and renal involvement is rare. We present the case of an 81-year-old woman on PTU treatment due to toxic nodular goitre who developed alveolar hemorrhage and rapidly progressive glomerulonephritis. The authors highlight the importance of early recognising drug-induced pulmonary-renal syndrome (PRS) in order to avoid unnecessary tests, a delay in the diagnosis and evolution to end-stage kidney disease or life-threatening conditions.
publishDate 2015
dc.date.none.fl_str_mv 2015-10-22T12:16:02Z
2015
2015-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.17/2315
url http://hdl.handle.net/10400.17/2315
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Reumatologia
publisher.none.fl_str_mv Sociedade Portuguesa de Reumatologia
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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