Paraquat poisoning in a medical ward

Bibliographic Details
Main Author: Santos, José Manuel
Publication Date: 1996
Other Authors: Santos, Arsénio, Simão, Adélia, Almiro, Eurico, Severo, Franscisco, Porto, Armando
Format: Article
Language: por
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://revista.spmi.pt/index.php/rpmi/article/view/2270
Summary: The authors present a retrospective study of paraquat poisoning cases admitted at an Inter­nal Medicine department of a central hospital. This analysis includes a 7.5 years period, invol­ving 26 cases, with male sex predominance (16 patients) and ages between 16 and 74 years old. The mean time elapsed between the toxic ingesti­on andflrst health care was 1,8 hours if they were admitted in the first 24 hours; three patients ar­rived later to the hospital. The quantities of poi­son ingested were variable, but more frequently between 20 and 100 ml Thirteen in-patients were death while the other 13 were discharged from hospital with good health (known middle survi­ val time of 10 months). The 2 groups were com­ pared and the single prognostic factor was the ingested quantity of paraquat. Dyspnea, oliguria and jaundice were the clinical manifestations with prognostic value, while values of LDH, AST and pO2 (at admission on Urgency Room) were also prognostic indicators. Any medical measure see­ med to modify the disease course when a high dose was ingested.
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spelling Paraquat poisoning in a medical wardlntoxicação pelo Paraquat: Casuística dum serviço de Medicina InternaparaquatintoxicaçãoparaquatpoisoningThe authors present a retrospective study of paraquat poisoning cases admitted at an Inter­nal Medicine department of a central hospital. This analysis includes a 7.5 years period, invol­ving 26 cases, with male sex predominance (16 patients) and ages between 16 and 74 years old. The mean time elapsed between the toxic ingesti­on andflrst health care was 1,8 hours if they were admitted in the first 24 hours; three patients ar­rived later to the hospital. The quantities of poi­son ingested were variable, but more frequently between 20 and 100 ml Thirteen in-patients were death while the other 13 were discharged from hospital with good health (known middle survi­ val time of 10 months). The 2 groups were com­ pared and the single prognostic factor was the ingested quantity of paraquat. Dyspnea, oliguria and jaundice were the clinical manifestations with prognostic value, while values of LDH, AST and pO2 (at admission on Urgency Room) were also prognostic indicators. Any medical measure see­ med to modify the disease course when a high dose was ingested.Os autores apresentam uma análise retrospec­tiva dos casos de intoxicação por paraquat in­ternados num serviço de Medicina Interna dum hospital central. O estudo engloba um período de 7,5 anos, incluindo 26 casos, 16 homens e 10 mu­lheres, com idades compreendidas entre os 16 e os 74 anos. O tempo médio decorrido entre a in­gestão do tóxico e a prestação dos primeiros cuidados médicos foi, nos doentes que recorre­ram nas primeiras 24 horas, de 1,8 horas, ha­vendo 3 que só mais tarde recorreram ao hospi­tal. As quantidades de tóxico ingeridas foram calculadas segundo os dados fornecidos pelos doentes e mostraram uma grande dispersão, ten­do, no entanto, a maior parte deles ingerido en­tre 20 e 100 ml. Durante o internamento, falece­ram 13 doentes (50%), que tiveram uma sobrevi­vência média de 7 dias. Os restantes 13 doentes tiveram alta hospitalar, tendo uma sobrevivên­cia média conhecida de 10 meses. Foram comparados entre si os grupos dos doentes falecidos e dos sobreviventes, concluin­do-se que o factor decisivo para a mortalidade foi a quantidade de tóxico ingerida. O apareci­mento de dispneia, oligúria ou icterícia foi indi­cador de mau prognóstico, enquanto os valores laboratoriais, à entrada no Serviço de Urgência, de LDH, TGO e pCO estavam significativamente mais alterados nos doentes que vieram a falecer. Quando a dose ingerida foi elevada, as medidas terapêuticas, mesmo as mais agressivas, não alteraram o curso da doença. Finalmente, os auto­res discutem os resultados encontrados, compa­rando-os com os de outros estudos.Sociedade Portuguesa de Medicina Interna1996-06-28info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://revista.spmi.pt/index.php/rpmi/article/view/2270Internal Medicine; Vol. 3 No. 2 (1996): Abril/ Junho; 74-80Medicina Interna; Vol. 3 N.º 2 (1996): Abril/ Junho; 74-802183-99800872-671Xreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPporhttps://revista.spmi.pt/index.php/rpmi/article/view/2270https://revista.spmi.pt/index.php/rpmi/article/view/2270/1640Santos, José ManuelSantos, ArsénioSimão, AdéliaAlmiro, EuricoSevero, FransciscoPorto, Armandoinfo:eu-repo/semantics/openAccess2023-08-19T06:11:46Zoai:oai.revista.spmi.pt:article/2270Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T11:05:29.646804Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Paraquat poisoning in a medical ward
lntoxicação pelo Paraquat: Casuística dum serviço de Medicina Interna
title Paraquat poisoning in a medical ward
spellingShingle Paraquat poisoning in a medical ward
Santos, José Manuel
paraquat
intoxicação
paraquat
poisoning
title_short Paraquat poisoning in a medical ward
title_full Paraquat poisoning in a medical ward
title_fullStr Paraquat poisoning in a medical ward
title_full_unstemmed Paraquat poisoning in a medical ward
title_sort Paraquat poisoning in a medical ward
author Santos, José Manuel
author_facet Santos, José Manuel
Santos, Arsénio
Simão, Adélia
Almiro, Eurico
Severo, Franscisco
Porto, Armando
author_role author
author2 Santos, Arsénio
Simão, Adélia
Almiro, Eurico
Severo, Franscisco
Porto, Armando
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Santos, José Manuel
Santos, Arsénio
Simão, Adélia
Almiro, Eurico
Severo, Franscisco
Porto, Armando
dc.subject.por.fl_str_mv paraquat
intoxicação
paraquat
poisoning
topic paraquat
intoxicação
paraquat
poisoning
description The authors present a retrospective study of paraquat poisoning cases admitted at an Inter­nal Medicine department of a central hospital. This analysis includes a 7.5 years period, invol­ving 26 cases, with male sex predominance (16 patients) and ages between 16 and 74 years old. The mean time elapsed between the toxic ingesti­on andflrst health care was 1,8 hours if they were admitted in the first 24 hours; three patients ar­rived later to the hospital. The quantities of poi­son ingested were variable, but more frequently between 20 and 100 ml Thirteen in-patients were death while the other 13 were discharged from hospital with good health (known middle survi­ val time of 10 months). The 2 groups were com­ pared and the single prognostic factor was the ingested quantity of paraquat. Dyspnea, oliguria and jaundice were the clinical manifestations with prognostic value, while values of LDH, AST and pO2 (at admission on Urgency Room) were also prognostic indicators. Any medical measure see­ med to modify the disease course when a high dose was ingested.
publishDate 1996
dc.date.none.fl_str_mv 1996-06-28
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://revista.spmi.pt/index.php/rpmi/article/view/2270
url https://revista.spmi.pt/index.php/rpmi/article/view/2270
dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv https://revista.spmi.pt/index.php/rpmi/article/view/2270
https://revista.spmi.pt/index.php/rpmi/article/view/2270/1640
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Medicina Interna
publisher.none.fl_str_mv Sociedade Portuguesa de Medicina Interna
dc.source.none.fl_str_mv Internal Medicine; Vol. 3 No. 2 (1996): Abril/ Junho; 74-80
Medicina Interna; Vol. 3 N.º 2 (1996): Abril/ Junho; 74-80
2183-9980
0872-671X
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