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Endoscopic ultrasound with fine needle aspiration is useful in pancreatic cysts smaller than 3 cm

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Main Author: Faias, Sandra
Publication Date: 2020
Other Authors: Cravo, Marília, Pereira da Silva, João, Chaves, Paula, Dias Pereira, A.
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10451/45297
Summary: The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creat iveco mmons .org/licen ses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creat ivecommons .org/publi cdoma in/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data
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spelling Endoscopic ultrasound with fine needle aspiration is useful in pancreatic cysts smaller than 3 cmCEAPancreatic cystEUS-FNAIPMNMCNSmall sizeThe Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creat iveco mmons .org/licen ses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creat ivecommons .org/publi cdoma in/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the dataBackground: In current guidelines, endoscopic ultrasound with fne-needle aspiration (EUS-FNA) is recommended in pancreatic cystic lesions (PCLs) with worrisome features (size≥3 cm, mural nodule, or Wirsung dilation). Objective: To evaluate the diagnostic ability and assess the accuracy of EUS-FNA in PCLs smaller than 3 cm. Methods: Retrospective study of PCLs<3 cm (2007–2016) undergoing EUS-FNA. Clinical, EUS and pancreatic cystic fuid (PCF) data were prospectively registered. Performance of EUS-FNA with PCF analysis for the detection of malignancy and accuracy in surgical cohort were analyzed. Results: We evaluated 115 patients with PCLs<3 cm who underwent EUS-FNA. 19 patients underwent surgery, 7 had malignant, 8 pre-malignant, and the remaining 4 benign lesions. Mass/mural nodule was present in 27% of the cysts, CEA level was higher than 192 ng/mL in 39.4% of patients, and only 35% of cytologic samples were informative. Nevertheless, additional FNA for PCF analysis improved the diagnostic performance of EUS imaging—AUC=0.80 versus AUC=60. Conclusion: EUS-FNA has good accuracy in PCLs<3 cm. It confrmed malignancy even in lesions without worrisome features (nodule/mass), with two in every fve resections showing high-risk/malignant lesions. EUS-FNA was also useful to diagnose benign cysts, possibly allowing surveillance to be stopped in one in every fve patients.This study was supported by a Research Grant from Sociedade Portuguesa de Endoscopia Digestiva in 2018 that had no role in any stage of the study, from design to submission for publication.Springer NatureRepositório da Universidade de LisboaFaias, SandraCravo, MaríliaPereira da Silva, JoãoChaves, PaulaDias Pereira, A.2020-12-14T15:24:26Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/45297engBMC Gastroenterol 20, 413 (2020)10.1186/s12876-020-01565-91471-230Xinfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-17T14:25:56Zoai:repositorio.ulisboa.pt:10451/45297Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T03:11:40.675729Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Endoscopic ultrasound with fine needle aspiration is useful in pancreatic cysts smaller than 3 cm
title Endoscopic ultrasound with fine needle aspiration is useful in pancreatic cysts smaller than 3 cm
spellingShingle Endoscopic ultrasound with fine needle aspiration is useful in pancreatic cysts smaller than 3 cm
Faias, Sandra
CEA
Pancreatic cyst
EUS-FNA
IPMN
MCN
Small size
title_short Endoscopic ultrasound with fine needle aspiration is useful in pancreatic cysts smaller than 3 cm
title_full Endoscopic ultrasound with fine needle aspiration is useful in pancreatic cysts smaller than 3 cm
title_fullStr Endoscopic ultrasound with fine needle aspiration is useful in pancreatic cysts smaller than 3 cm
title_full_unstemmed Endoscopic ultrasound with fine needle aspiration is useful in pancreatic cysts smaller than 3 cm
title_sort Endoscopic ultrasound with fine needle aspiration is useful in pancreatic cysts smaller than 3 cm
author Faias, Sandra
author_facet Faias, Sandra
Cravo, Marília
Pereira da Silva, João
Chaves, Paula
Dias Pereira, A.
author_role author
author2 Cravo, Marília
Pereira da Silva, João
Chaves, Paula
Dias Pereira, A.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Faias, Sandra
Cravo, Marília
Pereira da Silva, João
Chaves, Paula
Dias Pereira, A.
dc.subject.por.fl_str_mv CEA
Pancreatic cyst
EUS-FNA
IPMN
MCN
Small size
topic CEA
Pancreatic cyst
EUS-FNA
IPMN
MCN
Small size
description The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creat iveco mmons .org/licen ses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creat ivecommons .org/publi cdoma in/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data
publishDate 2020
dc.date.none.fl_str_mv 2020-12-14T15:24:26Z
2020
2020-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/45297
url http://hdl.handle.net/10451/45297
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv BMC Gastroenterol 20, 413 (2020)
10.1186/s12876-020-01565-9
1471-230X
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eu_rights_str_mv openAccess
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publisher.none.fl_str_mv Springer Nature
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instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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