Antioxidant activity and cytotoxicity of solubilized C60 and its conjugates with butylated hydroxytoluene

Bibliographic Details
Main Author: Nunes, A. S.
Publication Date: 2011
Other Authors: Matias, A., Caetano, Liliana Aranha, Graça, Anabela, Simplício, Ana Luísa
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.21/1947
Summary: It has been described that fullerenes (C60) present interesting properties with potential application in clinical conditions related to oxidative stress. One of the most prominent features of fullerenes is the ability to quench free radicals. However, because of its poor solubility, this has been studied mostly in organic solutions, while the antioxidant activity and cytotoxicity of fullerenes and their derivates in aqueous medium is not well characterized. The antioxidant capacity of synthesised C60-conjugates has been investigated and its was higher comparing to C60 isolated. The aim of this study was to assess the viability of C60-conjugates by determining its antioxidant activity and cytotoxicity in bio-relevant media.
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spelling Antioxidant activity and cytotoxicity of solubilized C60 and its conjugates with butylated hydroxytolueneFarmáciaPharmacyAntioxidant activityCytotoxicitySolubilized C60Butylated hydroxytolueneIt has been described that fullerenes (C60) present interesting properties with potential application in clinical conditions related to oxidative stress. One of the most prominent features of fullerenes is the ability to quench free radicals. However, because of its poor solubility, this has been studied mostly in organic solutions, while the antioxidant activity and cytotoxicity of fullerenes and their derivates in aqueous medium is not well characterized. The antioxidant capacity of synthesised C60-conjugates has been investigated and its was higher comparing to C60 isolated. The aim of this study was to assess the viability of C60-conjugates by determining its antioxidant activity and cytotoxicity in bio-relevant media.Escola Superior de Tecnologia da Saúde de LisboaRCIPLNunes, A. S.Matias, A.Caetano, Liliana AranhaGraça, AnabelaSimplício, Ana Luísa2012-11-19T10:49:33Z2011-102011-10-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10400.21/1947enginfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-02-12T09:50:05Zoai:repositorio.ipl.pt:10400.21/1947Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T20:02:53.354070Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Antioxidant activity and cytotoxicity of solubilized C60 and its conjugates with butylated hydroxytoluene
title Antioxidant activity and cytotoxicity of solubilized C60 and its conjugates with butylated hydroxytoluene
spellingShingle Antioxidant activity and cytotoxicity of solubilized C60 and its conjugates with butylated hydroxytoluene
Nunes, A. S.
Farmácia
Pharmacy
Antioxidant activity
Cytotoxicity
Solubilized C60
Butylated hydroxytoluene
title_short Antioxidant activity and cytotoxicity of solubilized C60 and its conjugates with butylated hydroxytoluene
title_full Antioxidant activity and cytotoxicity of solubilized C60 and its conjugates with butylated hydroxytoluene
title_fullStr Antioxidant activity and cytotoxicity of solubilized C60 and its conjugates with butylated hydroxytoluene
title_full_unstemmed Antioxidant activity and cytotoxicity of solubilized C60 and its conjugates with butylated hydroxytoluene
title_sort Antioxidant activity and cytotoxicity of solubilized C60 and its conjugates with butylated hydroxytoluene
author Nunes, A. S.
author_facet Nunes, A. S.
Matias, A.
Caetano, Liliana Aranha
Graça, Anabela
Simplício, Ana Luísa
author_role author
author2 Matias, A.
Caetano, Liliana Aranha
Graça, Anabela
Simplício, Ana Luísa
author2_role author
author
author
author
dc.contributor.none.fl_str_mv RCIPL
dc.contributor.author.fl_str_mv Nunes, A. S.
Matias, A.
Caetano, Liliana Aranha
Graça, Anabela
Simplício, Ana Luísa
dc.subject.por.fl_str_mv Farmácia
Pharmacy
Antioxidant activity
Cytotoxicity
Solubilized C60
Butylated hydroxytoluene
topic Farmácia
Pharmacy
Antioxidant activity
Cytotoxicity
Solubilized C60
Butylated hydroxytoluene
description It has been described that fullerenes (C60) present interesting properties with potential application in clinical conditions related to oxidative stress. One of the most prominent features of fullerenes is the ability to quench free radicals. However, because of its poor solubility, this has been studied mostly in organic solutions, while the antioxidant activity and cytotoxicity of fullerenes and their derivates in aqueous medium is not well characterized. The antioxidant capacity of synthesised C60-conjugates has been investigated and its was higher comparing to C60 isolated. The aim of this study was to assess the viability of C60-conjugates by determining its antioxidant activity and cytotoxicity in bio-relevant media.
publishDate 2011
dc.date.none.fl_str_mv 2011-10
2011-10-01T00:00:00Z
2012-11-19T10:49:33Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.21/1947
url http://hdl.handle.net/10400.21/1947
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Escola Superior de Tecnologia da Saúde de Lisboa
publisher.none.fl_str_mv Escola Superior de Tecnologia da Saúde de Lisboa
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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