When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis

Bibliographic Details
Main Author: Hilário Soldin, Inês
Publication Date: 2024
Other Authors: Nunes, Ana Luísa, Dias, Paulo, Sousa, Fausto, Estevinho, Fernanda
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://doi.org/10.32932/gecp.2023.10.039
Summary: Superior vena cava syndrome is an oncological emergency. It is life-threatening in 15% of the cases. When it is severe and the presentation form of malignancy, a multidisciplinary diagnostic and therapeutic approach is challenging and urgent. We present the case of a patient with no previous cancer that came to the emergency department due to superior vena cava syndrome. He had oedema of the face, cervical region and upper limbs, dyspnoea and altered mental status. Chest computed tomography showed a superior vena cava syndrome secondary to a mediastinal mass. Considering the severity of the obstruction, the absence of histological diagnosis and distant metastasis, an endovascular stent was placed urgently, with rapid clinical improvement. Subsequently, we obtained a diagnosis of stage IIIA lung adenocarcinoma. After partial response to chemoradiotherapy, the patient started consolidation therapy with durvalumab. Six months after the diagnosis, there is no relapse.
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spelling When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosisQuando o stent na abordagem do síndrome da veia cava superior permite o tratamento radical do cancro de pulmão de não pequenas células ao diagnósticoNon-small cell lung cancersuperior vena cava syndromeendovascular stentradiotherapyCancro do pulmão de não pequenas célulassíndrome da veia cava superiorstent endovascularradioterapiaSuperior vena cava syndrome is an oncological emergency. It is life-threatening in 15% of the cases. When it is severe and the presentation form of malignancy, a multidisciplinary diagnostic and therapeutic approach is challenging and urgent. We present the case of a patient with no previous cancer that came to the emergency department due to superior vena cava syndrome. He had oedema of the face, cervical region and upper limbs, dyspnoea and altered mental status. Chest computed tomography showed a superior vena cava syndrome secondary to a mediastinal mass. Considering the severity of the obstruction, the absence of histological diagnosis and distant metastasis, an endovascular stent was placed urgently, with rapid clinical improvement. Subsequently, we obtained a diagnosis of stage IIIA lung adenocarcinoma. After partial response to chemoradiotherapy, the patient started consolidation therapy with durvalumab. Six months after the diagnosis, there is no relapse.O síndrome da veia cava superior é uma emergência oncológica. Em 15% dos casos causa risco imediato de vida. Quando é a forma de apresentação da doença oncológica e apresenta critérios de gravidade, a abordagem diagnóstica e terapêutica multidisciplinar é desafiante e urgente. Apresentamos o caso de um doente sem diagnóstico oncológico prévio, com síndrome da veia cava superior. Apresentava edema da face, região cervical e membros superiores, dispneia e alteração do estado mental. Realizada tomografia computadorizada de tórax, que evidenciou um síndrome da veia cava superior secundário a massa mediastínica. Considerando a gravidade da obstrução, ausência de diagnóstico histológico e de metastização no restante estudo imagiológico realizado no serviço de urgência, optou-se pela colocação de stent endovascular de urgência, com rápida melhoria clínica. Confirmou-se o diagnóstico de adenocarcinoma pulmonar estadio IIIA. Após resposta parcial a quimioradioterapia, iniciou terapêutica de consolidação com durvalumab. Sem recidiva seis meses após o diagnóstico.Grupo de Estudos de Cancro do Pulmão (GECP)2024-12-27info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.32932/gecp.2023.10.039https://doi.org/10.32932/gecp.2023.10.039Thoracic Cancer Journal; Vol. 20 No. 1 (2023); 41-46reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPenghttps://thoracjournal.com/index.php/tcj/article/view/26https://thoracjournal.com/index.php/tcj/article/view/26/21Copyright (c) 2024 Author(s) (or their employer(s)) and THORAC 2024info:eu-repo/semantics/openAccessHilário Soldin, InêsNunes, Ana LuísaDias, PauloSousa, FaustoEstevinho, Fernanda2025-01-22T08:57:15Zoai:ojs.thoracjournal.com:article/26Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T19:40:59.060825Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis
Quando o stent na abordagem do síndrome da veia cava superior permite o tratamento radical do cancro de pulmão de não pequenas células ao diagnóstico
title When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis
spellingShingle When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis
Hilário Soldin, Inês
Non-small cell lung cancer
superior vena cava syndrome
endovascular stent
radiotherapy
Cancro do pulmão de não pequenas células
síndrome da veia cava superior
stent endovascular
radioterapia
title_short When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis
title_full When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis
title_fullStr When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis
title_full_unstemmed When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis
title_sort When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis
author Hilário Soldin, Inês
author_facet Hilário Soldin, Inês
Nunes, Ana Luísa
Dias, Paulo
Sousa, Fausto
Estevinho, Fernanda
author_role author
author2 Nunes, Ana Luísa
Dias, Paulo
Sousa, Fausto
Estevinho, Fernanda
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Hilário Soldin, Inês
Nunes, Ana Luísa
Dias, Paulo
Sousa, Fausto
Estevinho, Fernanda
dc.subject.por.fl_str_mv Non-small cell lung cancer
superior vena cava syndrome
endovascular stent
radiotherapy
Cancro do pulmão de não pequenas células
síndrome da veia cava superior
stent endovascular
radioterapia
topic Non-small cell lung cancer
superior vena cava syndrome
endovascular stent
radiotherapy
Cancro do pulmão de não pequenas células
síndrome da veia cava superior
stent endovascular
radioterapia
description Superior vena cava syndrome is an oncological emergency. It is life-threatening in 15% of the cases. When it is severe and the presentation form of malignancy, a multidisciplinary diagnostic and therapeutic approach is challenging and urgent. We present the case of a patient with no previous cancer that came to the emergency department due to superior vena cava syndrome. He had oedema of the face, cervical region and upper limbs, dyspnoea and altered mental status. Chest computed tomography showed a superior vena cava syndrome secondary to a mediastinal mass. Considering the severity of the obstruction, the absence of histological diagnosis and distant metastasis, an endovascular stent was placed urgently, with rapid clinical improvement. Subsequently, we obtained a diagnosis of stage IIIA lung adenocarcinoma. After partial response to chemoradiotherapy, the patient started consolidation therapy with durvalumab. Six months after the diagnosis, there is no relapse.
publishDate 2024
dc.date.none.fl_str_mv 2024-12-27
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.32932/gecp.2023.10.039
https://doi.org/10.32932/gecp.2023.10.039
url https://doi.org/10.32932/gecp.2023.10.039
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://thoracjournal.com/index.php/tcj/article/view/26
https://thoracjournal.com/index.php/tcj/article/view/26/21
dc.rights.driver.fl_str_mv Copyright (c) 2024 Author(s) (or their employer(s)) and THORAC 2024
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2024 Author(s) (or their employer(s)) and THORAC 2024
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Grupo de Estudos de Cancro do Pulmão (GECP)
publisher.none.fl_str_mv Grupo de Estudos de Cancro do Pulmão (GECP)
dc.source.none.fl_str_mv Thoracic Cancer Journal; Vol. 20 No. 1 (2023); 41-46
reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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