When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis
Main Author: | |
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Publication Date: | 2024 |
Other Authors: | , , , |
Format: | Article |
Language: | eng |
Source: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
Download full: | https://doi.org/10.32932/gecp.2023.10.039 |
Summary: | Superior vena cava syndrome is an oncological emergency. It is life-threatening in 15% of the cases. When it is severe and the presentation form of malignancy, a multidisciplinary diagnostic and therapeutic approach is challenging and urgent. We present the case of a patient with no previous cancer that came to the emergency department due to superior vena cava syndrome. He had oedema of the face, cervical region and upper limbs, dyspnoea and altered mental status. Chest computed tomography showed a superior vena cava syndrome secondary to a mediastinal mass. Considering the severity of the obstruction, the absence of histological diagnosis and distant metastasis, an endovascular stent was placed urgently, with rapid clinical improvement. Subsequently, we obtained a diagnosis of stage IIIA lung adenocarcinoma. After partial response to chemoradiotherapy, the patient started consolidation therapy with durvalumab. Six months after the diagnosis, there is no relapse. |
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When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosisQuando o stent na abordagem do síndrome da veia cava superior permite o tratamento radical do cancro de pulmão de não pequenas células ao diagnósticoNon-small cell lung cancersuperior vena cava syndromeendovascular stentradiotherapyCancro do pulmão de não pequenas célulassíndrome da veia cava superiorstent endovascularradioterapiaSuperior vena cava syndrome is an oncological emergency. It is life-threatening in 15% of the cases. When it is severe and the presentation form of malignancy, a multidisciplinary diagnostic and therapeutic approach is challenging and urgent. We present the case of a patient with no previous cancer that came to the emergency department due to superior vena cava syndrome. He had oedema of the face, cervical region and upper limbs, dyspnoea and altered mental status. Chest computed tomography showed a superior vena cava syndrome secondary to a mediastinal mass. Considering the severity of the obstruction, the absence of histological diagnosis and distant metastasis, an endovascular stent was placed urgently, with rapid clinical improvement. Subsequently, we obtained a diagnosis of stage IIIA lung adenocarcinoma. After partial response to chemoradiotherapy, the patient started consolidation therapy with durvalumab. Six months after the diagnosis, there is no relapse.O síndrome da veia cava superior é uma emergência oncológica. Em 15% dos casos causa risco imediato de vida. Quando é a forma de apresentação da doença oncológica e apresenta critérios de gravidade, a abordagem diagnóstica e terapêutica multidisciplinar é desafiante e urgente. Apresentamos o caso de um doente sem diagnóstico oncológico prévio, com síndrome da veia cava superior. Apresentava edema da face, região cervical e membros superiores, dispneia e alteração do estado mental. Realizada tomografia computadorizada de tórax, que evidenciou um síndrome da veia cava superior secundário a massa mediastínica. Considerando a gravidade da obstrução, ausência de diagnóstico histológico e de metastização no restante estudo imagiológico realizado no serviço de urgência, optou-se pela colocação de stent endovascular de urgência, com rápida melhoria clínica. Confirmou-se o diagnóstico de adenocarcinoma pulmonar estadio IIIA. Após resposta parcial a quimioradioterapia, iniciou terapêutica de consolidação com durvalumab. Sem recidiva seis meses após o diagnóstico.Grupo de Estudos de Cancro do Pulmão (GECP)2024-12-27info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.32932/gecp.2023.10.039https://doi.org/10.32932/gecp.2023.10.039Thoracic Cancer Journal; Vol. 20 No. 1 (2023); 41-46reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPenghttps://thoracjournal.com/index.php/tcj/article/view/26https://thoracjournal.com/index.php/tcj/article/view/26/21Copyright (c) 2024 Author(s) (or their employer(s)) and THORAC 2024info:eu-repo/semantics/openAccessHilário Soldin, InêsNunes, Ana LuísaDias, PauloSousa, FaustoEstevinho, Fernanda2025-01-22T08:57:15Zoai:ojs.thoracjournal.com:article/26Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T19:40:59.060825Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
dc.title.none.fl_str_mv |
When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis Quando o stent na abordagem do síndrome da veia cava superior permite o tratamento radical do cancro de pulmão de não pequenas células ao diagnóstico |
title |
When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis |
spellingShingle |
When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis Hilário Soldin, Inês Non-small cell lung cancer superior vena cava syndrome endovascular stent radiotherapy Cancro do pulmão de não pequenas células síndrome da veia cava superior stent endovascular radioterapia |
title_short |
When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis |
title_full |
When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis |
title_fullStr |
When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis |
title_full_unstemmed |
When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis |
title_sort |
When the stenting in the approach to superior vena cava syndrome allows radical treatment of non-small cell lung cancer at the diagnosis |
author |
Hilário Soldin, Inês |
author_facet |
Hilário Soldin, Inês Nunes, Ana Luísa Dias, Paulo Sousa, Fausto Estevinho, Fernanda |
author_role |
author |
author2 |
Nunes, Ana Luísa Dias, Paulo Sousa, Fausto Estevinho, Fernanda |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Hilário Soldin, Inês Nunes, Ana Luísa Dias, Paulo Sousa, Fausto Estevinho, Fernanda |
dc.subject.por.fl_str_mv |
Non-small cell lung cancer superior vena cava syndrome endovascular stent radiotherapy Cancro do pulmão de não pequenas células síndrome da veia cava superior stent endovascular radioterapia |
topic |
Non-small cell lung cancer superior vena cava syndrome endovascular stent radiotherapy Cancro do pulmão de não pequenas células síndrome da veia cava superior stent endovascular radioterapia |
description |
Superior vena cava syndrome is an oncological emergency. It is life-threatening in 15% of the cases. When it is severe and the presentation form of malignancy, a multidisciplinary diagnostic and therapeutic approach is challenging and urgent. We present the case of a patient with no previous cancer that came to the emergency department due to superior vena cava syndrome. He had oedema of the face, cervical region and upper limbs, dyspnoea and altered mental status. Chest computed tomography showed a superior vena cava syndrome secondary to a mediastinal mass. Considering the severity of the obstruction, the absence of histological diagnosis and distant metastasis, an endovascular stent was placed urgently, with rapid clinical improvement. Subsequently, we obtained a diagnosis of stage IIIA lung adenocarcinoma. After partial response to chemoradiotherapy, the patient started consolidation therapy with durvalumab. Six months after the diagnosis, there is no relapse. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-12-27 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.32932/gecp.2023.10.039 https://doi.org/10.32932/gecp.2023.10.039 |
url |
https://doi.org/10.32932/gecp.2023.10.039 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://thoracjournal.com/index.php/tcj/article/view/26 https://thoracjournal.com/index.php/tcj/article/view/26/21 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2024 Author(s) (or their employer(s)) and THORAC 2024 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2024 Author(s) (or their employer(s)) and THORAC 2024 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Grupo de Estudos de Cancro do Pulmão (GECP) |
publisher.none.fl_str_mv |
Grupo de Estudos de Cancro do Pulmão (GECP) |
dc.source.none.fl_str_mv |
Thoracic Cancer Journal; Vol. 20 No. 1 (2023); 41-46 reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia instacron:RCAAP |
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FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
collection |
Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
repository.name.fl_str_mv |
Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia |
repository.mail.fl_str_mv |
info@rcaap.pt |
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