Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide

Bibliographic Details
Main Author: Santos, A. Sofia
Publication Date: 2023
Other Authors: Ferro, Rita D., Viduedo, Nuno, Maia, Luísa B., Silva, Artur M. S., Marques, M. Manuel B.
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/150333
Summary: The National NMR Facility is supported by FCT, ROTEIRO/0031/2013-PINFRA/22161/2016, co-financed by FEDER through COMPETE2020, POCI, and PORLandFCT through PIDDAC) and CERMAX(022162).
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network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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spelling Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxidebis(indolyl)methanesindoletBuOKradicalsbenzylalcoholsChemistry(all)The National NMR Facility is supported by FCT, ROTEIRO/0031/2013-PINFRA/22161/2016, co-financed by FEDER through COMPETE2020, POCI, and PORLandFCT through PIDDAC) and CERMAX(022162).The indole moiety is an important N-heterocycle found in natural products, and a key structural component of many value-added chemicals including pharmaceuticals. In particular, bis(3-indolyl)methanes (BIMs) are an important subgroup of indoles, composed of two indole units. Herein, we report the development of a simple method to access BIMs derivatives in yields of up to 77 % by exploiting a tBuOK-mediated coupling reaction of indoles and benzyl alcohols.LAQV@REQUIMTEDQ - Departamento de QuímicaRUNSantos, A. SofiaFerro, Rita D.Viduedo, NunoMaia, Luísa B.Silva, Artur M. S.Marques, M. Manuel B.2023-03-10T22:51:11Z2023-012023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article7application/pdfhttp://hdl.handle.net/10362/150333eng2191-1363PURE: 50901166https://doi.org/10.1002/open.202200265info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T18:09:49Zoai:run.unl.pt:10362/150333Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:40:09.244636Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
title Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
spellingShingle Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
Santos, A. Sofia
bis(indolyl)methanes
indole
tBuOK
radicals
benzylalcohols
Chemistry(all)
title_short Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
title_full Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
title_fullStr Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
title_full_unstemmed Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
title_sort Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
author Santos, A. Sofia
author_facet Santos, A. Sofia
Ferro, Rita D.
Viduedo, Nuno
Maia, Luísa B.
Silva, Artur M. S.
Marques, M. Manuel B.
author_role author
author2 Ferro, Rita D.
Viduedo, Nuno
Maia, Luísa B.
Silva, Artur M. S.
Marques, M. Manuel B.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv LAQV@REQUIMTE
DQ - Departamento de Química
RUN
dc.contributor.author.fl_str_mv Santos, A. Sofia
Ferro, Rita D.
Viduedo, Nuno
Maia, Luísa B.
Silva, Artur M. S.
Marques, M. Manuel B.
dc.subject.por.fl_str_mv bis(indolyl)methanes
indole
tBuOK
radicals
benzylalcohols
Chemistry(all)
topic bis(indolyl)methanes
indole
tBuOK
radicals
benzylalcohols
Chemistry(all)
description The National NMR Facility is supported by FCT, ROTEIRO/0031/2013-PINFRA/22161/2016, co-financed by FEDER through COMPETE2020, POCI, and PORLandFCT through PIDDAC) and CERMAX(022162).
publishDate 2023
dc.date.none.fl_str_mv 2023-03-10T22:51:11Z
2023-01
2023-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/150333
url http://hdl.handle.net/10362/150333
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2191-1363
PURE: 50901166
https://doi.org/10.1002/open.202200265
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 7
application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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