Brugada Syndrome and Exercise

Bibliographic Details
Main Author: Gonçalves, Carolina
Publication Date: 2025
Other Authors: Vazão, Adriana, Ferreira Carvalho, Mariana, Cabral, Margarida, Faustino Martins, André Manuel, Amado, Mónica, Pereira, Joana, Saraiva, Fátima, Martins, Hélia, Dores, Helder
Format: Other
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/182078
Summary: Publisher Copyright: © 2025 by the authors.
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spelling Brugada Syndrome and ExerciseIs It Time for a Paradigm Change?athletesBrugada syndromeexerciseimplantable cardioverter defibrillatorsportssudden cardiac deathPharmacology, Toxicology and Pharmaceutics(all)Pharmacology (medical)SDG 3 - Good Health and Well-beingPublisher Copyright: © 2025 by the authors.Background: Despite the multiple benefits of exercise for health, exercise in the presence of arrhythmic disorders can trigger adverse clinical events, including sudden cardiac death (SCD). The aim of this narrative review is to summarize the most recent recommendations regarding physical activity and exercise in individuals with Brugada Syndrome (BrS). Methods: An advanced literature search was performed on the Pubmed and clinicaltrials.gov databases and published articles/clinical trials registered until September 2024 were analyzed. The final analysis included 33 articles. Results: Despite initial reports suggesting a higher risk of SCD in BrS, the risk is not as high as expected, and there is no evidence that exercise is an independent predictor. Therefore, scientific recommendations have become less restrictive. However, consensus on risk scores is lacking, making the evaluation of BrS a real challenge. The most recent recommendations emphasize individual evaluation, risk stratification, shared decision-making, and general preventive measures, allowing asymptomatic BrS patients as well as genotype positive/phenotype negative patients to participate in competitive sports, excluding sports under extreme conditions. Regarding patients with an implantable cardioverter defibrillator, both leisure and competitive sports may be considered in asymptomatic patients, avoiding contact sports. Conclusions: Research on the relationship between exercise and cardiovascular disease is evolving, but evidence-based recommendations for sports in BrS patients are scarce and further studies are needed.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Laboratório Associado de Translacção e Inovação para a Saúde Global - LA Real (Pólo NMS)Comprehensive Health Research Centre (CHRC) - pólo NMSRUNGonçalves, CarolinaVazão, AdrianaFerreira Carvalho, MarianaCabral, MargaridaFaustino Martins, André ManuelAmado, MónicaPereira, JoanaSaraiva, FátimaMartins, HéliaDores, Helder2025-04-10T16:01:07Z2025-032025-03-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttp://hdl.handle.net/10362/182078eng2308-3425PURE: 114326802https://doi.org/10.3390/jcdd12030094info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-04-28T01:33:24Zoai:run.unl.pt:10362/182078Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T06:26:01.418219Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Brugada Syndrome and Exercise
Is It Time for a Paradigm Change?
title Brugada Syndrome and Exercise
spellingShingle Brugada Syndrome and Exercise
Gonçalves, Carolina
athletes
Brugada syndrome
exercise
implantable cardioverter defibrillator
sports
sudden cardiac death
Pharmacology, Toxicology and Pharmaceutics(all)
Pharmacology (medical)
SDG 3 - Good Health and Well-being
title_short Brugada Syndrome and Exercise
title_full Brugada Syndrome and Exercise
title_fullStr Brugada Syndrome and Exercise
title_full_unstemmed Brugada Syndrome and Exercise
title_sort Brugada Syndrome and Exercise
author Gonçalves, Carolina
author_facet Gonçalves, Carolina
Vazão, Adriana
Ferreira Carvalho, Mariana
Cabral, Margarida
Faustino Martins, André Manuel
Amado, Mónica
Pereira, Joana
Saraiva, Fátima
Martins, Hélia
Dores, Helder
author_role author
author2 Vazão, Adriana
Ferreira Carvalho, Mariana
Cabral, Margarida
Faustino Martins, André Manuel
Amado, Mónica
Pereira, Joana
Saraiva, Fátima
Martins, Hélia
Dores, Helder
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
Laboratório Associado de Translacção e Inovação para a Saúde Global - LA Real (Pólo NMS)
Comprehensive Health Research Centre (CHRC) - pólo NMS
RUN
dc.contributor.author.fl_str_mv Gonçalves, Carolina
Vazão, Adriana
Ferreira Carvalho, Mariana
Cabral, Margarida
Faustino Martins, André Manuel
Amado, Mónica
Pereira, Joana
Saraiva, Fátima
Martins, Hélia
Dores, Helder
dc.subject.por.fl_str_mv athletes
Brugada syndrome
exercise
implantable cardioverter defibrillator
sports
sudden cardiac death
Pharmacology, Toxicology and Pharmaceutics(all)
Pharmacology (medical)
SDG 3 - Good Health and Well-being
topic athletes
Brugada syndrome
exercise
implantable cardioverter defibrillator
sports
sudden cardiac death
Pharmacology, Toxicology and Pharmaceutics(all)
Pharmacology (medical)
SDG 3 - Good Health and Well-being
description Publisher Copyright: © 2025 by the authors.
publishDate 2025
dc.date.none.fl_str_mv 2025-04-10T16:01:07Z
2025-03
2025-03-01T00:00:00Z
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url http://hdl.handle.net/10362/182078
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2308-3425
PURE: 114326802
https://doi.org/10.3390/jcdd12030094
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