Single cell analysis of toxinogenesis by vegetative and sporulating cells in the enteric pathogen Clostridioides difficile

Bibliographic Details
Main Author: Cassona, CP
Publication Date: 2018
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/99027
Summary: "Clostridium difficile, recently re-classified as Clostridioides difficile, is a strict anaerobe, with the ability to form spores. C. difficile is also a major nosocomial enteric pathogen worldwide and the cause of severe gastrointestinal conditions that can lead to death. The oxygenresistant spores allow host-host transmission, but also persistence of the organism in the host and the environment, being linked to disease recurrence. The last two decades have witnessed the emergence of epidemic strains that increased the incidence of C. difficile infection (CDI) associated with more severe symptoms and high recurrence rates.(...)"
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spelling Single cell analysis of toxinogenesis by vegetative and sporulating cells in the enteric pathogen Clostridioides difficiletoxinogenesisClostridioides difficileBiology"Clostridium difficile, recently re-classified as Clostridioides difficile, is a strict anaerobe, with the ability to form spores. C. difficile is also a major nosocomial enteric pathogen worldwide and the cause of severe gastrointestinal conditions that can lead to death. The oxygenresistant spores allow host-host transmission, but also persistence of the organism in the host and the environment, being linked to disease recurrence. The last two decades have witnessed the emergence of epidemic strains that increased the incidence of C. difficile infection (CDI) associated with more severe symptoms and high recurrence rates.(...)"Henriques, AdrianoSerrano, MónicaRUNCassona, CP2022-01-31T01:30:22Z2019-012018-112019-01-01T00:00:00Zdoctoral thesisinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10362/99027enginfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T17:43:57Zoai:run.unl.pt:10362/99027Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:15:09.635492Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Single cell analysis of toxinogenesis by vegetative and sporulating cells in the enteric pathogen Clostridioides difficile
title Single cell analysis of toxinogenesis by vegetative and sporulating cells in the enteric pathogen Clostridioides difficile
spellingShingle Single cell analysis of toxinogenesis by vegetative and sporulating cells in the enteric pathogen Clostridioides difficile
Cassona, CP
toxinogenesis
Clostridioides difficile
Biology
title_short Single cell analysis of toxinogenesis by vegetative and sporulating cells in the enteric pathogen Clostridioides difficile
title_full Single cell analysis of toxinogenesis by vegetative and sporulating cells in the enteric pathogen Clostridioides difficile
title_fullStr Single cell analysis of toxinogenesis by vegetative and sporulating cells in the enteric pathogen Clostridioides difficile
title_full_unstemmed Single cell analysis of toxinogenesis by vegetative and sporulating cells in the enteric pathogen Clostridioides difficile
title_sort Single cell analysis of toxinogenesis by vegetative and sporulating cells in the enteric pathogen Clostridioides difficile
author Cassona, CP
author_facet Cassona, CP
author_role author
dc.contributor.none.fl_str_mv Henriques, Adriano
Serrano, Mónica
RUN
dc.contributor.author.fl_str_mv Cassona, CP
dc.subject.por.fl_str_mv toxinogenesis
Clostridioides difficile
Biology
topic toxinogenesis
Clostridioides difficile
Biology
description "Clostridium difficile, recently re-classified as Clostridioides difficile, is a strict anaerobe, with the ability to form spores. C. difficile is also a major nosocomial enteric pathogen worldwide and the cause of severe gastrointestinal conditions that can lead to death. The oxygenresistant spores allow host-host transmission, but also persistence of the organism in the host and the environment, being linked to disease recurrence. The last two decades have witnessed the emergence of epidemic strains that increased the incidence of C. difficile infection (CDI) associated with more severe symptoms and high recurrence rates.(...)"
publishDate 2018
dc.date.none.fl_str_mv 2018-11
2019-01
2019-01-01T00:00:00Z
2022-01-31T01:30:22Z
dc.type.driver.fl_str_mv doctoral thesis
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/99027
url http://hdl.handle.net/10362/99027
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833596554747838464

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