Insights into the production of toxins and the assembly of spores in Clostridioides difficile

Detalhes bibliográficos
Autor(a) principal: Ramalhete, Sara
Data de Publicação: 2021
Idioma: eng
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: http://hdl.handle.net/10362/123468
Resumo: "Clostridioides difficile, a strict anaerobe, sporeforming bacterium, is a major nosocomial pathogen, causing a range of intestinal conditions linked to antibiotic therapy. Because of the number of infections and deaths it causes yearly, the high recurrence rates, the spreading at the community level and the risk of zoonotic transmission, it is classified as an urgent threat by the Centres for Disease Control and Prevention (CDC). Toxins and spores, two of the most important virulence factors in C. difficile, are key elements to determine the severity of the disease and the spreading of the infection, respectively.(...)"
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spelling Insights into the production of toxins and the assembly of spores in Clostridioides difficileClostridioides difficileToxinsBiology"Clostridioides difficile, a strict anaerobe, sporeforming bacterium, is a major nosocomial pathogen, causing a range of intestinal conditions linked to antibiotic therapy. Because of the number of infections and deaths it causes yearly, the high recurrence rates, the spreading at the community level and the risk of zoonotic transmission, it is classified as an urgent threat by the Centres for Disease Control and Prevention (CDC). Toxins and spores, two of the most important virulence factors in C. difficile, are key elements to determine the severity of the disease and the spreading of the infection, respectively.(...)"Henriques, Adriano OliveiraRUNRamalhete, Sara2024-07-27T00:31:59Z2021-07-272021-062021-07-27T00:00:00Zdoctoral thesisinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10362/123468enginfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-08-05T01:33:12Zoai:run.unl.pt:10362/123468Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:26:27.704341Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Insights into the production of toxins and the assembly of spores in Clostridioides difficile
title Insights into the production of toxins and the assembly of spores in Clostridioides difficile
spellingShingle Insights into the production of toxins and the assembly of spores in Clostridioides difficile
Ramalhete, Sara
Clostridioides difficile
Toxins
Biology
title_short Insights into the production of toxins and the assembly of spores in Clostridioides difficile
title_full Insights into the production of toxins and the assembly of spores in Clostridioides difficile
title_fullStr Insights into the production of toxins and the assembly of spores in Clostridioides difficile
title_full_unstemmed Insights into the production of toxins and the assembly of spores in Clostridioides difficile
title_sort Insights into the production of toxins and the assembly of spores in Clostridioides difficile
author Ramalhete, Sara
author_facet Ramalhete, Sara
author_role author
dc.contributor.none.fl_str_mv Henriques, Adriano Oliveira
RUN
dc.contributor.author.fl_str_mv Ramalhete, Sara
dc.subject.por.fl_str_mv Clostridioides difficile
Toxins
Biology
topic Clostridioides difficile
Toxins
Biology
description "Clostridioides difficile, a strict anaerobe, sporeforming bacterium, is a major nosocomial pathogen, causing a range of intestinal conditions linked to antibiotic therapy. Because of the number of infections and deaths it causes yearly, the high recurrence rates, the spreading at the community level and the risk of zoonotic transmission, it is classified as an urgent threat by the Centres for Disease Control and Prevention (CDC). Toxins and spores, two of the most important virulence factors in C. difficile, are key elements to determine the severity of the disease and the spreading of the infection, respectively.(...)"
publishDate 2021
dc.date.none.fl_str_mv 2021-07-27
2021-06
2021-07-27T00:00:00Z
2024-07-27T00:31:59Z
dc.type.driver.fl_str_mv doctoral thesis
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/123468
url http://hdl.handle.net/10362/123468
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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