O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto
Main Author: | |
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Publication Date: | 2019 |
Format: | Master thesis |
Language: | por |
Source: | Biblioteca Digital de Teses e Dissertações da Uninove |
Download full: | http://bibliotecatede.uninove.br/handle/tede/2322 |
Summary: | Multiple sclerosis is an autoimmune disease of the central nervous system, characterized by inflammation and destruction of the myelin sheath. Fatigue is one of the main symptoms noticed by patients, impacts with quality of life and has few treatment options. Photobiomodulation is used in a variety of inflammatory conditions and may be beneficial in the treatment of multiple sclerosis fatigue. Objective: To conduct a pilot study to analyze the effect of photobiomodulation in the treatment of fatigue and symptoms reported by patients with recurrent remitting multiple sclerosis. Method: Participants was recruited from UNINOVE integrated health outpatient clinic, randomized and allocated into two groups: Group 1, sublingual application; Group 2, radial artery application. Fatigue was analyzed by the modified fatigue impact scale. In addition, each participant described which more limiting symptoms they had over the past 3 months and which ones observed improvement in the last days. The protocol was performed twice a week for 3 months. Results: Modified fatigue impact scale scores showed significant reduction after treatment in group 1 (p <0.05) and slight decrease in group 2 (p> 0.05), analysis by the Mann-Whitney test. The mentioned symptoms in the evaluations was fatigue, headache, muscle pain and paresthesia. Of these, fatigue and muscle pain showed significant improvement (p <0.05) after treatment. Conclusion: Photobiomodulation could be a viable resource in the management of fatigue in people with recurrent remitting multiple sclerosis, because the applied in the sublingual region significantly decreased the scores of the assessment scale used and both applications decreased the fatigue reported by patients, although muscle pain, headache and paresthesia did not improve with the proposed treatment. |
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Bussadori, Sandra KalilBussadori, Sandra Kalilhttp://lattes.cnpq.br/2923609110540503Alencar, Raquel Candido2020-10-28T21:04:01Z2019-12-18Alencar, Raquel Candido. O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto. 2019. 54 f. Dissertação( Programa de Pós-Graduação em Ciências da Reabilitação) - Universidade Nove de Julho, São Paulo.http://bibliotecatede.uninove.br/handle/tede/2322Multiple sclerosis is an autoimmune disease of the central nervous system, characterized by inflammation and destruction of the myelin sheath. Fatigue is one of the main symptoms noticed by patients, impacts with quality of life and has few treatment options. Photobiomodulation is used in a variety of inflammatory conditions and may be beneficial in the treatment of multiple sclerosis fatigue. Objective: To conduct a pilot study to analyze the effect of photobiomodulation in the treatment of fatigue and symptoms reported by patients with recurrent remitting multiple sclerosis. Method: Participants was recruited from UNINOVE integrated health outpatient clinic, randomized and allocated into two groups: Group 1, sublingual application; Group 2, radial artery application. Fatigue was analyzed by the modified fatigue impact scale. In addition, each participant described which more limiting symptoms they had over the past 3 months and which ones observed improvement in the last days. The protocol was performed twice a week for 3 months. Results: Modified fatigue impact scale scores showed significant reduction after treatment in group 1 (p <0.05) and slight decrease in group 2 (p> 0.05), analysis by the Mann-Whitney test. The mentioned symptoms in the evaluations was fatigue, headache, muscle pain and paresthesia. Of these, fatigue and muscle pain showed significant improvement (p <0.05) after treatment. Conclusion: Photobiomodulation could be a viable resource in the management of fatigue in people with recurrent remitting multiple sclerosis, because the applied in the sublingual region significantly decreased the scores of the assessment scale used and both applications decreased the fatigue reported by patients, although muscle pain, headache and paresthesia did not improve with the proposed treatment.A esclerose múltipla é uma doença auto imune do sistema nervoso central, caracterizada por inflamação e destruição da bainha de mielina. A fadiga é um dos principais sintomas apresentados pelos pacientes, interfere na qualidade de vida e possuem poucas opções de tratamento. A fotobiomodulação é utilizada em diversas condições inflamatórias e pode ser benéfica no tratamento da fadiga na esclerose múltipla. Objetivo: Realizar um estudo piloto para analisar o efeito da fotobiomodulação no tratamento de fadiga e sintomas referidos por pacientes com esclerose múltipla remitente recorrente. Método: Os participantes foram recrutados no ambulatório integrado de saúde da UNINOVE, randomizados e alocados em dois grupos: Grupo 1, aplicação na região sublingual; Grupo 2, aplicação na artéria radial. A fadiga foi analisada pela escala modificada do impacto da fadiga. Além disso, cada participante descreveu quais sintomas mais limitantes eles apresentaram nos últimos 3 meses e quais observaram melhora nos últimos dias. O protocolo foi realizado 2 vezes na semana durante 3 meses. Resultados: Os escores da escala modificada de impacto da fadiga apresentaram redução significativa após tratamento no grupo 1 (p<0,05) e discreta diminuição no grupo 2 (p>0,05), análise através do teste Mann-Whitney. Os sintomas citados nas avaliações foram: fadiga, cefaleia, dor muscular e parestesia. Destes, fadiga apresentou melhora significativa (p<0,05) após tratamento. Conclusão: A fotobiomodulação pode ser um recurso viável na gestão da fadiga em pessoas com esclerose múltipla remitente recorrente, pois a aplicada na região sublingual diminuiu significativamente os escores da escala de avaliação utilizada e ambas as aplicações diminuíram a fadiga relatada pelos pacientes, embora dor muscular, cefaleia e parestesia não apresentaram melhora com o tratamento proposto.Submitted by Nadir Basilio (nadirsb@uninove.br) on 2020-10-28T21:04:01Z No. of bitstreams: 1 RAQUEL CÂNDIDO ALENCAR.pdf: 743040 bytes, checksum: 588142e8e6f25c26403b95ff6c4e9ccc (MD5)Made available in DSpace on 2020-10-28T21:04:01Z (GMT). No. of bitstreams: 1 RAQUEL CÂNDIDO ALENCAR.pdf: 743040 bytes, checksum: 588142e8e6f25c26403b95ff6c4e9ccc (MD5) Previous issue date: 2019-12-18application/pdfporUniversidade Nove de JulhoPrograma de Pós-Graduação em Ciências da ReabilitaçãoUNINOVEBrasilSaúdeesclerose múltiplamodalidades de fisioterapiafadigasintomas da esclerose múltiplareabilitaçãophotobiomodulationmultiple sclerosisphysical therapy modalitiesfatiguemultiple sclerosis symptomsrehabilitationphotobiomodulationCIENCIAS DA SAUDEO efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo pilotoThe effect of photobiomodulation on fatigue and symptoms referred to in individuals with recurrent remitting multiple sclerosis - pilot studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis8765449414823306929600info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da Uninoveinstname:Universidade Nove de Julho (UNINOVE)instacron:UNINOVEORIGINALRAQUEL CÂNDIDO ALENCAR.pdfRAQUEL CÂNDIDO ALENCAR.pdfapplication/pdf743040http://localhost:8080/tede/bitstream/tede/2322/2/RAQUEL+C%C3%82NDIDO+ALENCAR.pdf588142e8e6f25c26403b95ff6c4e9cccMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://localhost:8080/tede/bitstream/tede/2322/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede/23222020-10-28 19:04:01.579oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttp://bibliotecatede.uninove.br/PRIhttp://bibliotecatede.uninove.br/oai/requestbibliotecatede@uninove.br||bibliotecatede@uninove.bropendoar:2020-10-28T21:04:01Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE)false |
dc.title.por.fl_str_mv |
O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto |
dc.title.alternative.eng.fl_str_mv |
The effect of photobiomodulation on fatigue and symptoms referred to in individuals with recurrent remitting multiple sclerosis - pilot study |
title |
O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto |
spellingShingle |
O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto Alencar, Raquel Candido esclerose múltipla modalidades de fisioterapia fadiga sintomas da esclerose múltipla reabilitação photobiomodulation multiple sclerosis physical therapy modalities fatigue multiple sclerosis symptoms rehabilitation photobiomodulation CIENCIAS DA SAUDE |
title_short |
O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto |
title_full |
O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto |
title_fullStr |
O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto |
title_full_unstemmed |
O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto |
title_sort |
O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto |
author |
Alencar, Raquel Candido |
author_facet |
Alencar, Raquel Candido |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Bussadori, Sandra Kalil |
dc.contributor.referee1.fl_str_mv |
Bussadori, Sandra Kalil |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/2923609110540503 |
dc.contributor.author.fl_str_mv |
Alencar, Raquel Candido |
contributor_str_mv |
Bussadori, Sandra Kalil Bussadori, Sandra Kalil |
dc.subject.por.fl_str_mv |
esclerose múltipla modalidades de fisioterapia fadiga sintomas da esclerose múltipla reabilitação photobiomodulation |
topic |
esclerose múltipla modalidades de fisioterapia fadiga sintomas da esclerose múltipla reabilitação photobiomodulation multiple sclerosis physical therapy modalities fatigue multiple sclerosis symptoms rehabilitation photobiomodulation CIENCIAS DA SAUDE |
dc.subject.eng.fl_str_mv |
multiple sclerosis physical therapy modalities fatigue multiple sclerosis symptoms rehabilitation photobiomodulation |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
description |
Multiple sclerosis is an autoimmune disease of the central nervous system, characterized by inflammation and destruction of the myelin sheath. Fatigue is one of the main symptoms noticed by patients, impacts with quality of life and has few treatment options. Photobiomodulation is used in a variety of inflammatory conditions and may be beneficial in the treatment of multiple sclerosis fatigue. Objective: To conduct a pilot study to analyze the effect of photobiomodulation in the treatment of fatigue and symptoms reported by patients with recurrent remitting multiple sclerosis. Method: Participants was recruited from UNINOVE integrated health outpatient clinic, randomized and allocated into two groups: Group 1, sublingual application; Group 2, radial artery application. Fatigue was analyzed by the modified fatigue impact scale. In addition, each participant described which more limiting symptoms they had over the past 3 months and which ones observed improvement in the last days. The protocol was performed twice a week for 3 months. Results: Modified fatigue impact scale scores showed significant reduction after treatment in group 1 (p <0.05) and slight decrease in group 2 (p> 0.05), analysis by the Mann-Whitney test. The mentioned symptoms in the evaluations was fatigue, headache, muscle pain and paresthesia. Of these, fatigue and muscle pain showed significant improvement (p <0.05) after treatment. Conclusion: Photobiomodulation could be a viable resource in the management of fatigue in people with recurrent remitting multiple sclerosis, because the applied in the sublingual region significantly decreased the scores of the assessment scale used and both applications decreased the fatigue reported by patients, although muscle pain, headache and paresthesia did not improve with the proposed treatment. |
publishDate |
2019 |
dc.date.issued.fl_str_mv |
2019-12-18 |
dc.date.accessioned.fl_str_mv |
2020-10-28T21:04:01Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Alencar, Raquel Candido. O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto. 2019. 54 f. Dissertação( Programa de Pós-Graduação em Ciências da Reabilitação) - Universidade Nove de Julho, São Paulo. |
dc.identifier.uri.fl_str_mv |
http://bibliotecatede.uninove.br/handle/tede/2322 |
identifier_str_mv |
Alencar, Raquel Candido. O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto. 2019. 54 f. Dissertação( Programa de Pós-Graduação em Ciências da Reabilitação) - Universidade Nove de Julho, São Paulo. |
url |
http://bibliotecatede.uninove.br/handle/tede/2322 |
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por |
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por |
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8765449414823306929 |
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600 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Universidade Nove de Julho |
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Programa de Pós-Graduação em Ciências da Reabilitação |
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UNINOVE |
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Brasil |
dc.publisher.department.fl_str_mv |
Saúde |
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Universidade Nove de Julho |
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