O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto

Bibliographic Details
Main Author: Alencar, Raquel Candido
Publication Date: 2019
Format: Master thesis
Language: por
Source: Biblioteca Digital de Teses e Dissertações da Uninove
Download full: http://bibliotecatede.uninove.br/handle/tede/2322
Summary: Multiple sclerosis is an autoimmune disease of the central nervous system, characterized by inflammation and destruction of the myelin sheath. Fatigue is one of the main symptoms noticed by patients, impacts with quality of life and has few treatment options. Photobiomodulation is used in a variety of inflammatory conditions and may be beneficial in the treatment of multiple sclerosis fatigue. Objective: To conduct a pilot study to analyze the effect of photobiomodulation in the treatment of fatigue and symptoms reported by patients with recurrent remitting multiple sclerosis. Method: Participants was recruited from UNINOVE integrated health outpatient clinic, randomized and allocated into two groups: Group 1, sublingual application; Group 2, radial artery application. Fatigue was analyzed by the modified fatigue impact scale. In addition, each participant described which more limiting symptoms they had over the past 3 months and which ones observed improvement in the last days. The protocol was performed twice a week for 3 months. Results: Modified fatigue impact scale scores showed significant reduction after treatment in group 1 (p <0.05) and slight decrease in group 2 (p> 0.05), analysis by the Mann-Whitney test. The mentioned symptoms in the evaluations was fatigue, headache, muscle pain and paresthesia. Of these, fatigue and muscle pain showed significant improvement (p <0.05) after treatment. Conclusion: Photobiomodulation could be a viable resource in the management of fatigue in people with recurrent remitting multiple sclerosis, because the applied in the sublingual region significantly decreased the scores of the assessment scale used and both applications decreased the fatigue reported by patients, although muscle pain, headache and paresthesia did not improve with the proposed treatment.
id NOVE_e7f48fafc62a19db9e38788d8cae712c
oai_identifier_str oai:localhost:tede/2322
network_acronym_str NOVE
network_name_str Biblioteca Digital de Teses e Dissertações da Uninove
repository_id_str
spelling Bussadori, Sandra KalilBussadori, Sandra Kalilhttp://lattes.cnpq.br/2923609110540503Alencar, Raquel Candido2020-10-28T21:04:01Z2019-12-18Alencar, Raquel Candido. O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto. 2019. 54 f. Dissertação( Programa de Pós-Graduação em Ciências da Reabilitação) - Universidade Nove de Julho, São Paulo.http://bibliotecatede.uninove.br/handle/tede/2322Multiple sclerosis is an autoimmune disease of the central nervous system, characterized by inflammation and destruction of the myelin sheath. Fatigue is one of the main symptoms noticed by patients, impacts with quality of life and has few treatment options. Photobiomodulation is used in a variety of inflammatory conditions and may be beneficial in the treatment of multiple sclerosis fatigue. Objective: To conduct a pilot study to analyze the effect of photobiomodulation in the treatment of fatigue and symptoms reported by patients with recurrent remitting multiple sclerosis. Method: Participants was recruited from UNINOVE integrated health outpatient clinic, randomized and allocated into two groups: Group 1, sublingual application; Group 2, radial artery application. Fatigue was analyzed by the modified fatigue impact scale. In addition, each participant described which more limiting symptoms they had over the past 3 months and which ones observed improvement in the last days. The protocol was performed twice a week for 3 months. Results: Modified fatigue impact scale scores showed significant reduction after treatment in group 1 (p <0.05) and slight decrease in group 2 (p> 0.05), analysis by the Mann-Whitney test. The mentioned symptoms in the evaluations was fatigue, headache, muscle pain and paresthesia. Of these, fatigue and muscle pain showed significant improvement (p <0.05) after treatment. Conclusion: Photobiomodulation could be a viable resource in the management of fatigue in people with recurrent remitting multiple sclerosis, because the applied in the sublingual region significantly decreased the scores of the assessment scale used and both applications decreased the fatigue reported by patients, although muscle pain, headache and paresthesia did not improve with the proposed treatment.A esclerose múltipla é uma doença auto imune do sistema nervoso central, caracterizada por inflamação e destruição da bainha de mielina. A fadiga é um dos principais sintomas apresentados pelos pacientes, interfere na qualidade de vida e possuem poucas opções de tratamento. A fotobiomodulação é utilizada em diversas condições inflamatórias e pode ser benéfica no tratamento da fadiga na esclerose múltipla. Objetivo: Realizar um estudo piloto para analisar o efeito da fotobiomodulação no tratamento de fadiga e sintomas referidos por pacientes com esclerose múltipla remitente recorrente. Método: Os participantes foram recrutados no ambulatório integrado de saúde da UNINOVE, randomizados e alocados em dois grupos: Grupo 1, aplicação na região sublingual; Grupo 2, aplicação na artéria radial. A fadiga foi analisada pela escala modificada do impacto da fadiga. Além disso, cada participante descreveu quais sintomas mais limitantes eles apresentaram nos últimos 3 meses e quais observaram melhora nos últimos dias. O protocolo foi realizado 2 vezes na semana durante 3 meses. Resultados: Os escores da escala modificada de impacto da fadiga apresentaram redução significativa após tratamento no grupo 1 (p<0,05) e discreta diminuição no grupo 2 (p>0,05), análise através do teste Mann-Whitney. Os sintomas citados nas avaliações foram: fadiga, cefaleia, dor muscular e parestesia. Destes, fadiga apresentou melhora significativa (p<0,05) após tratamento. Conclusão: A fotobiomodulação pode ser um recurso viável na gestão da fadiga em pessoas com esclerose múltipla remitente recorrente, pois a aplicada na região sublingual diminuiu significativamente os escores da escala de avaliação utilizada e ambas as aplicações diminuíram a fadiga relatada pelos pacientes, embora dor muscular, cefaleia e parestesia não apresentaram melhora com o tratamento proposto.Submitted by Nadir Basilio (nadirsb@uninove.br) on 2020-10-28T21:04:01Z No. of bitstreams: 1 RAQUEL CÂNDIDO ALENCAR.pdf: 743040 bytes, checksum: 588142e8e6f25c26403b95ff6c4e9ccc (MD5)Made available in DSpace on 2020-10-28T21:04:01Z (GMT). No. of bitstreams: 1 RAQUEL CÂNDIDO ALENCAR.pdf: 743040 bytes, checksum: 588142e8e6f25c26403b95ff6c4e9ccc (MD5) Previous issue date: 2019-12-18application/pdfporUniversidade Nove de JulhoPrograma de Pós-Graduação em Ciências da ReabilitaçãoUNINOVEBrasilSaúdeesclerose múltiplamodalidades de fisioterapiafadigasintomas da esclerose múltiplareabilitaçãophotobiomodulationmultiple sclerosisphysical therapy modalitiesfatiguemultiple sclerosis symptomsrehabilitationphotobiomodulationCIENCIAS DA SAUDEO efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo pilotoThe effect of photobiomodulation on fatigue and symptoms referred to in individuals with recurrent remitting multiple sclerosis - pilot studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis8765449414823306929600info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da Uninoveinstname:Universidade Nove de Julho (UNINOVE)instacron:UNINOVEORIGINALRAQUEL CÂNDIDO ALENCAR.pdfRAQUEL CÂNDIDO ALENCAR.pdfapplication/pdf743040http://localhost:8080/tede/bitstream/tede/2322/2/RAQUEL+C%C3%82NDIDO+ALENCAR.pdf588142e8e6f25c26403b95ff6c4e9cccMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://localhost:8080/tede/bitstream/tede/2322/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede/23222020-10-28 19:04:01.579oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttp://bibliotecatede.uninove.br/PRIhttp://bibliotecatede.uninove.br/oai/requestbibliotecatede@uninove.br||bibliotecatede@uninove.bropendoar:2020-10-28T21:04:01Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE)false
dc.title.por.fl_str_mv O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto
dc.title.alternative.eng.fl_str_mv The effect of photobiomodulation on fatigue and symptoms referred to in individuals with recurrent remitting multiple sclerosis - pilot study
title O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto
spellingShingle O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto
Alencar, Raquel Candido
esclerose múltipla
modalidades de fisioterapia
fadiga
sintomas da esclerose múltipla
reabilitação
photobiomodulation
multiple sclerosis
physical therapy modalities
fatigue
multiple sclerosis symptoms
rehabilitation
photobiomodulation
CIENCIAS DA SAUDE
title_short O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto
title_full O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto
title_fullStr O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto
title_full_unstemmed O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto
title_sort O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto
author Alencar, Raquel Candido
author_facet Alencar, Raquel Candido
author_role author
dc.contributor.advisor1.fl_str_mv Bussadori, Sandra Kalil
dc.contributor.referee1.fl_str_mv Bussadori, Sandra Kalil
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/2923609110540503
dc.contributor.author.fl_str_mv Alencar, Raquel Candido
contributor_str_mv Bussadori, Sandra Kalil
Bussadori, Sandra Kalil
dc.subject.por.fl_str_mv esclerose múltipla
modalidades de fisioterapia
fadiga
sintomas da esclerose múltipla
reabilitação
photobiomodulation
topic esclerose múltipla
modalidades de fisioterapia
fadiga
sintomas da esclerose múltipla
reabilitação
photobiomodulation
multiple sclerosis
physical therapy modalities
fatigue
multiple sclerosis symptoms
rehabilitation
photobiomodulation
CIENCIAS DA SAUDE
dc.subject.eng.fl_str_mv multiple sclerosis
physical therapy modalities
fatigue
multiple sclerosis symptoms
rehabilitation
photobiomodulation
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE
description Multiple sclerosis is an autoimmune disease of the central nervous system, characterized by inflammation and destruction of the myelin sheath. Fatigue is one of the main symptoms noticed by patients, impacts with quality of life and has few treatment options. Photobiomodulation is used in a variety of inflammatory conditions and may be beneficial in the treatment of multiple sclerosis fatigue. Objective: To conduct a pilot study to analyze the effect of photobiomodulation in the treatment of fatigue and symptoms reported by patients with recurrent remitting multiple sclerosis. Method: Participants was recruited from UNINOVE integrated health outpatient clinic, randomized and allocated into two groups: Group 1, sublingual application; Group 2, radial artery application. Fatigue was analyzed by the modified fatigue impact scale. In addition, each participant described which more limiting symptoms they had over the past 3 months and which ones observed improvement in the last days. The protocol was performed twice a week for 3 months. Results: Modified fatigue impact scale scores showed significant reduction after treatment in group 1 (p <0.05) and slight decrease in group 2 (p> 0.05), analysis by the Mann-Whitney test. The mentioned symptoms in the evaluations was fatigue, headache, muscle pain and paresthesia. Of these, fatigue and muscle pain showed significant improvement (p <0.05) after treatment. Conclusion: Photobiomodulation could be a viable resource in the management of fatigue in people with recurrent remitting multiple sclerosis, because the applied in the sublingual region significantly decreased the scores of the assessment scale used and both applications decreased the fatigue reported by patients, although muscle pain, headache and paresthesia did not improve with the proposed treatment.
publishDate 2019
dc.date.issued.fl_str_mv 2019-12-18
dc.date.accessioned.fl_str_mv 2020-10-28T21:04:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv Alencar, Raquel Candido. O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto. 2019. 54 f. Dissertação( Programa de Pós-Graduação em Ciências da Reabilitação) - Universidade Nove de Julho, São Paulo.
dc.identifier.uri.fl_str_mv http://bibliotecatede.uninove.br/handle/tede/2322
identifier_str_mv Alencar, Raquel Candido. O efeito da fotobiomodulação na fadiga e sintomas referidos em indivíduos com esclerose múltipla remitente recorrente– estudo piloto. 2019. 54 f. Dissertação( Programa de Pós-Graduação em Ciências da Reabilitação) - Universidade Nove de Julho, São Paulo.
url http://bibliotecatede.uninove.br/handle/tede/2322
dc.language.iso.fl_str_mv por
language por
dc.relation.cnpq.fl_str_mv 8765449414823306929
dc.relation.confidence.fl_str_mv 600
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Nove de Julho
dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Ciências da Reabilitação
dc.publisher.initials.fl_str_mv UNINOVE
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Saúde
publisher.none.fl_str_mv Universidade Nove de Julho
dc.source.none.fl_str_mv reponame:Biblioteca Digital de Teses e Dissertações da Uninove
instname:Universidade Nove de Julho (UNINOVE)
instacron:UNINOVE
instname_str Universidade Nove de Julho (UNINOVE)
instacron_str UNINOVE
institution UNINOVE
reponame_str Biblioteca Digital de Teses e Dissertações da Uninove
collection Biblioteca Digital de Teses e Dissertações da Uninove
bitstream.url.fl_str_mv http://localhost:8080/tede/bitstream/tede/2322/2/RAQUEL+C%C3%82NDIDO+ALENCAR.pdf
http://localhost:8080/tede/bitstream/tede/2322/1/license.txt
bitstream.checksum.fl_str_mv 588142e8e6f25c26403b95ff6c4e9ccc
bd3efa91386c1718a7f26a329fdcb468
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
repository.name.fl_str_mv Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE)
repository.mail.fl_str_mv bibliotecatede@uninove.br||bibliotecatede@uninove.br
_version_ 1841206968897765376