Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results
| Main Author: | |
|---|---|
| Publication Date: | 2008 |
| Other Authors: | , , , , |
| Format: | Article |
| Language: | eng |
| Source: | Repositório Institucional da FIOCRUZ (ARCA) |
| DOI: | 10.1590/S0037-86822008000700019 |
| Download full: | https://arca.fiocruz.br/handle/icict/55155 |
Summary: | Neste estudo, a expressão de receptores de quimiocinas na superfície dos leucócitos circulantes foi feita pela citometria de fluxo. Houve aumento da porcentagem de linfócitos CCR2+CD4+ no sangue periférico dos pacientes com hanseníase. Este resultado preliminar sugeriu alteração do perfil dos receptores de quimiocinas desses pacientes. |
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Mendonca, Vanessa AmaralTeixeira, Antônio LúcioMelo, Gustavo Eustáquio Brito Alvim deTeixeira, Mauro MartinsMartins Filho, Olindo AssisAntunes, Carlos MaurícioTeixeira, Antônio Lúcio2022-10-14T18:38:39Z2022-10-14T18:38:39Z2008MENDONÇA, Vanessa Amaral et al. Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results. Rev Soc Bras Med Trop., v. 41, Suppl 2, p. 95-98, 2008. doi: 10.1590/s0037-86822008000700019.0037-8682https://arca.fiocruz.br/handle/icict/5515510.1590/S0037-86822008000700019Neste estudo, a expressão de receptores de quimiocinas na superfície dos leucócitos circulantes foi feita pela citometria de fluxo. Houve aumento da porcentagem de linfócitos CCR2+CD4+ no sangue periférico dos pacientes com hanseníase. Este resultado preliminar sugeriu alteração do perfil dos receptores de quimiocinas desses pacientes.In this study, the expression of chemokine receptors on the surface of circulating leukocytes was determined using flow cytometry. An increase in the percentage of CCR2+CD4+ lymphocytes was observed in the peripheral blood of leprosy patients. This preliminary data suggests that alterations occur in die chemokine receptor profile of these patientsUniversidade Federal dos Vales de Jequitinhonha e Mucuri. Diamantina, MG, BrasilUniversidade Federal dos Vales de Jequitinhonha e Mucuri. Diamantina, MG, BrasilUniversidade Federal de Minas Gerais. Belo Horizonte, MG, BrasilFundação Oswaldo Cruz. Instituto Rene Rachou. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Belo Horizonte, MG, BrasilengSociedade Brasileira de Medicina TropicalHanseníaseReceptores de quimiocinaLeucócitosCitometria de fluxoLeprosyChemokine receptorsLeukocytesFlow cytometryAnalysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary resultsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALindex.pdfindex.pdfapplication/pdf199735https://arca.fiocruz.br/bitstreams/ec7c213c-02d2-4c40-b5e1-f6f549a50fb7/downloaddbbca32bdebf9799dc08cbdaee8bbe0dMD52trueAnonymousREADLICENSElicense.txttext/plain1748https://arca.fiocruz.br/bitstreams/6869afd4-6ac2-450f-ae8e-0836a1e9850b/download8a4605be74aa9ea9d79846c1fba20a33MD51falseAnonymousREADTEXTindex.pdf.txtindex.pdf.txtExtracted texttext/plain17455https://arca.fiocruz.br/bitstreams/9a1001bf-a3c8-4ec3-969d-d7ca44d8fd1e/downloadf07a834b0e58d9e94d98c13607b1a5fbMD55falseAnonymousREADTHUMBNAILindex.pdf.jpgindex.pdf.jpgGenerated Thumbnailimage/jpeg5631https://arca.fiocruz.br/bitstreams/f9efe11a-5248-4288-b95f-d23e620f2a7b/download85305af9520cf0d76b363e238f422896MD56falseAnonymousREADicict/551552025-07-29 21:00:00.88open.accessoai:arca.fiocruz.br:icict/55155https://arca.fiocruz.brRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352025-07-30T00:00Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)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 |
| dc.title.none.fl_str_mv |
Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results |
| title |
Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results |
| spellingShingle |
Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results Mendonca, Vanessa Amaral Hanseníase Receptores de quimiocina Leucócitos Citometria de fluxo Leprosy Chemokine receptors Leukocytes Flow cytometry |
| title_short |
Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results |
| title_full |
Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results |
| title_fullStr |
Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results |
| title_full_unstemmed |
Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results |
| title_sort |
Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results |
| author |
Mendonca, Vanessa Amaral |
| author_facet |
Mendonca, Vanessa Amaral Teixeira, Antônio Lúcio Melo, Gustavo Eustáquio Brito Alvim de Teixeira, Mauro Martins Martins Filho, Olindo Assis Antunes, Carlos Maurício |
| author_role |
author |
| author2 |
Teixeira, Antônio Lúcio Melo, Gustavo Eustáquio Brito Alvim de Teixeira, Mauro Martins Martins Filho, Olindo Assis Antunes, Carlos Maurício |
| author2_role |
author author author author author |
| dc.contributor.author.fl_str_mv |
Mendonca, Vanessa Amaral Teixeira, Antônio Lúcio Melo, Gustavo Eustáquio Brito Alvim de Teixeira, Mauro Martins Martins Filho, Olindo Assis Antunes, Carlos Maurício Teixeira, Antônio Lúcio |
| dc.subject.other.none.fl_str_mv |
Hanseníase Receptores de quimiocina Leucócitos Citometria de fluxo |
| topic |
Hanseníase Receptores de quimiocina Leucócitos Citometria de fluxo Leprosy Chemokine receptors Leukocytes Flow cytometry |
| dc.subject.en.none.fl_str_mv |
Leprosy Chemokine receptors Leukocytes Flow cytometry |
| description |
Neste estudo, a expressão de receptores de quimiocinas na superfície dos leucócitos circulantes foi feita pela citometria de fluxo. Houve aumento da porcentagem de linfócitos CCR2+CD4+ no sangue periférico dos pacientes com hanseníase. Este resultado preliminar sugeriu alteração do perfil dos receptores de quimiocinas desses pacientes. |
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2008 |
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2008 |
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2022-10-14T18:38:39Z |
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2022-10-14T18:38:39Z |
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info:eu-repo/semantics/article |
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MENDONÇA, Vanessa Amaral et al. Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results. Rev Soc Bras Med Trop., v. 41, Suppl 2, p. 95-98, 2008. doi: 10.1590/s0037-86822008000700019. |
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https://arca.fiocruz.br/handle/icict/55155 |
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0037-8682 |
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10.1590/S0037-86822008000700019 |
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MENDONÇA, Vanessa Amaral et al. Analysis of chemokine receptors on the surface of circulating leukocytes of individuals infected with Mycobacterium leprae: preliminary results. Rev Soc Bras Med Trop., v. 41, Suppl 2, p. 95-98, 2008. doi: 10.1590/s0037-86822008000700019. 0037-8682 10.1590/S0037-86822008000700019 |
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Sociedade Brasileira de Medicina Tropical |
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Sociedade Brasileira de Medicina Tropical |
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