Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment

Bibliographic Details
Main Author: Monteiro, Italo Gustavo Lima
Publication Date: 2021
Other Authors: Farias, Luis Arthur Brasil Gadelha, de Araújo, Ruth Maria Oliveira, Pontes, Licia Borges
Format: Article
Language: eng
Source: Journal of Health & Biological Sciences
DOI: 10.12662/2317-3076jhbs.v9i1.3545.p
Download full: https://periodicos.unichristus.edu.br/jhbs/article/view/3545
Summary: Introduction: Mucormycosis is an infection caused by the ubiquitous saprophyte fungi with rapid and aggressive progression, especially in immunocompromised patients. Case report: A 57-year-old woman diagnosed with rhino-orbital mucormycosis presented with decreased renal function after treatment with amphotericin B deoxycholate which was discontinued. Renal function improved after amphotericin B lipid-complex, being also treated with itraconazole, and otorhinolaryngological surgery. Conclusion: The use of Amphotericin B deoxycholate may result in adverse effects. In this situation, Amphotericin B lipid formulation is usually the drug of choice.
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spelling Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatmentCiências MédicasMucormycosis; Amphotericin B; Liposomal Formulation; Drug TherapyInfectious DiseasesIntroduction: Mucormycosis is an infection caused by the ubiquitous saprophyte fungi with rapid and aggressive progression, especially in immunocompromised patients. Case report: A 57-year-old woman diagnosed with rhino-orbital mucormycosis presented with decreased renal function after treatment with amphotericin B deoxycholate which was discontinued. Renal function improved after amphotericin B lipid-complex, being also treated with itraconazole, and otorhinolaryngological surgery. Conclusion: The use of Amphotericin B deoxycholate may result in adverse effects. In this situation, Amphotericin B lipid formulation is usually the drug of choice.Instituto para o Desenvolvimento da EducacaoMonteiro, Italo Gustavo LimaFarias, Luis Arthur Brasil Gadelhade Araújo, Ruth Maria OliveiraPontes, Licia Borges2021-06-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado por ParesRevisado por paresPeer Reviewapplication/pdfhttps://periodicos.unichristus.edu.br/jhbs/article/view/354510.12662/2317-3076jhbs.v9i1.3545.p%p.2021Journal of Health & Biological Sciences; v. 9, n. 1 (2021): Journal of Health and Biological Sciences; 1-4Journal of Health & Biological Sciences; v. 9, n. 1 (2021): Journal of Health and Biological Sciences; 1-4Journal of Health and Biological Sciences; v. 9, n. 1 (2021): Journal of Health and Biological Sciences; 1-42317-30762317-308410.12662/2317-3076jhbs.v9i1.2021reponame:Journal of Health & Biological Sciencesinstname:Centro Universitário Christus (Unichristus)instacron:CHRISTUSenghttps://periodicos.unichristus.edu.br/jhbs/article/view/3545/1362https://periodicos.unichristus.edu.br/jhbs/article/downloadSuppFile/3545/1009https://periodicos.unichristus.edu.br/jhbs/article/downloadSuppFile/3545/1010https://periodicos.unichristus.edu.br/jhbs/article/downloadSuppFile/3545/1011https://periodicos.unichristus.edu.br/jhbs/article/downloadSuppFile/3545/1012Ceará, Brasil.Direitos autorais 2021 Journal of Health & Biological Scienceshttp://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccess2021-12-30T20:32:16Zoai:ojs.unichristus.emnuvens.com.br:article/3545Revistahttps://periodicos.unichristus.edu.br/jhbs/indexPRIhttps://periodicos.unichristus.edu.br/jhbs/oaisecretaria.jhbs@unichristus.edu.br || editor.jhbs@fchristus.edu.br2317-30762317-3084opendoar:2023-01-13T09:47:28.991913Journal of Health & Biological Sciences - Centro Universitário Christus (Unichristus)true
dc.title.none.fl_str_mv Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment
title Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment
spellingShingle Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment
Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment
Monteiro, Italo Gustavo Lima
Ciências Médicas
Mucormycosis; Amphotericin B; Liposomal Formulation; Drug Therapy
Infectious Diseases
Monteiro, Italo Gustavo Lima
Ciências Médicas
Mucormycosis; Amphotericin B; Liposomal Formulation; Drug Therapy
Infectious Diseases
title_short Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment
title_full Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment
title_fullStr Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment
Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment
title_full_unstemmed Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment
Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment
title_sort Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment
author Monteiro, Italo Gustavo Lima
author_facet Monteiro, Italo Gustavo Lima
Monteiro, Italo Gustavo Lima
Farias, Luis Arthur Brasil Gadelha
de Araújo, Ruth Maria Oliveira
Pontes, Licia Borges
Farias, Luis Arthur Brasil Gadelha
de Araújo, Ruth Maria Oliveira
Pontes, Licia Borges
author_role author
author2 Farias, Luis Arthur Brasil Gadelha
de Araújo, Ruth Maria Oliveira
Pontes, Licia Borges
author2_role author
author
author
dc.contributor.none.fl_str_mv
dc.contributor.author.fl_str_mv Monteiro, Italo Gustavo Lima
Farias, Luis Arthur Brasil Gadelha
de Araújo, Ruth Maria Oliveira
Pontes, Licia Borges
dc.subject.por.fl_str_mv Ciências Médicas
Mucormycosis; Amphotericin B; Liposomal Formulation; Drug Therapy
Infectious Diseases
topic Ciências Médicas
Mucormycosis; Amphotericin B; Liposomal Formulation; Drug Therapy
Infectious Diseases
description Introduction: Mucormycosis is an infection caused by the ubiquitous saprophyte fungi with rapid and aggressive progression, especially in immunocompromised patients. Case report: A 57-year-old woman diagnosed with rhino-orbital mucormycosis presented with decreased renal function after treatment with amphotericin B deoxycholate which was discontinued. Renal function improved after amphotericin B lipid-complex, being also treated with itraconazole, and otorhinolaryngological surgery. Conclusion: The use of Amphotericin B deoxycholate may result in adverse effects. In this situation, Amphotericin B lipid formulation is usually the drug of choice.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-07
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado por Pares
Revisado por pares
Peer Review
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.unichristus.edu.br/jhbs/article/view/3545
10.12662/2317-3076jhbs.v9i1.3545.p%p.2021
url https://periodicos.unichristus.edu.br/jhbs/article/view/3545
identifier_str_mv 10.12662/2317-3076jhbs.v9i1.3545.p%p.2021
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://periodicos.unichristus.edu.br/jhbs/article/view/3545/1362
https://periodicos.unichristus.edu.br/jhbs/article/downloadSuppFile/3545/1009
https://periodicos.unichristus.edu.br/jhbs/article/downloadSuppFile/3545/1010
https://periodicos.unichristus.edu.br/jhbs/article/downloadSuppFile/3545/1011
https://periodicos.unichristus.edu.br/jhbs/article/downloadSuppFile/3545/1012
dc.rights.driver.fl_str_mv Direitos autorais 2021 Journal of Health & Biological Sciences
http://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos autorais 2021 Journal of Health & Biological Sciences
http://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.coverage.none.fl_str_mv Ceará, Brasil.
dc.publisher.none.fl_str_mv Instituto para o Desenvolvimento da Educacao
publisher.none.fl_str_mv Instituto para o Desenvolvimento da Educacao
dc.source.none.fl_str_mv Journal of Health & Biological Sciences; v. 9, n. 1 (2021): Journal of Health and Biological Sciences; 1-4
Journal of Health & Biological Sciences; v. 9, n. 1 (2021): Journal of Health and Biological Sciences; 1-4
Journal of Health and Biological Sciences; v. 9, n. 1 (2021): Journal of Health and Biological Sciences; 1-4
2317-3076
2317-3084
10.12662/2317-3076jhbs.v9i1.2021
reponame:Journal of Health & Biological Sciences
instname:Centro Universitário Christus (Unichristus)
instacron:CHRISTUS
instname_str Centro Universitário Christus (Unichristus)
instacron_str CHRISTUS
institution CHRISTUS
reponame_str Journal of Health & Biological Sciences
collection Journal of Health & Biological Sciences
repository.name.fl_str_mv Journal of Health & Biological Sciences - Centro Universitário Christus (Unichristus)
repository.mail.fl_str_mv secretaria.jhbs@unichristus.edu.br || editor.jhbs@fchristus.edu.br
_version_ 1822178658252488704
dc.identifier.doi.none.fl_str_mv 10.12662/2317-3076jhbs.v9i1.3545.p

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