Rhino-orbital-cerebral mucormycosis in a pediatric cancer patient

Detalhes bibliográficos
Autor(a) principal: Couto, Maria Eduarda
Data de Publicação: 2021
Outros Autores: Oliva, Tereza, Alberto, Pedro, Lebre, Ana, Pinto, Armando, Ferreira, Ana Maia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: http://hdl.handle.net/10400.16/2755
Resumo: Aim: Mucormycosis infections are highly lethal in immunosuppressed patients. The authors present a rare case of successful treatment of the condition. Case description: A 14-year-old male with acute lymphoblastic lymphoma in remission was diagnosed with pansinusitis, cerebral osteomyelitis, and encephalitis with an abscess caused by Rhizopus sp. Neurosurgical drainage, endoscopic sinus surgery, and left eye enucleation were performed, and the patient was simultaneously treated with lipossomal-amphotericin B and posaconazol (later replaced by isavuconazol). However, complications (left frontal lobe herniation and cerebrospinal fluid fistula) ensued, requiring surgical reoperation. Chemotherapy was restarted four months later. Comments: This is a rare case report, in which early and aggressive surgery, antifungal treatment, and multidisciplinary team work were crucial for the successful outcome.
id RCAP_ffd805961265aa8f3d3a09c3ce434ad4
oai_identifier_str oai:repositorio.chporto.pt:10400.16/2755
network_acronym_str RCAP
network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository_id_str https://opendoar.ac.uk/repository/7160
spelling Rhino-orbital-cerebral mucormycosis in a pediatric cancer patientMucormicose rino-orbito-cerebral num doente oncológico pediátricoantifungalencephalitismucormycosisosteomyelitisRhizopus spAim: Mucormycosis infections are highly lethal in immunosuppressed patients. The authors present a rare case of successful treatment of the condition. Case description: A 14-year-old male with acute lymphoblastic lymphoma in remission was diagnosed with pansinusitis, cerebral osteomyelitis, and encephalitis with an abscess caused by Rhizopus sp. Neurosurgical drainage, endoscopic sinus surgery, and left eye enucleation were performed, and the patient was simultaneously treated with lipossomal-amphotericin B and posaconazol (later replaced by isavuconazol). However, complications (left frontal lobe herniation and cerebrospinal fluid fistula) ensued, requiring surgical reoperation. Chemotherapy was restarted four months later. Comments: This is a rare case report, in which early and aggressive surgery, antifungal treatment, and multidisciplinary team work were crucial for the successful outcome.Centro Hospitalar Universitário do PortoRepositório Científico da Unidade Local de Saúde de Santo AntónioCouto, Maria EduardaOliva, TerezaAlberto, PedroLebre, AnaPinto, ArmandoFerreira, Ana Maia2022-11-30T10:41:49Z2021-122021-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.16/2755eng2183-9417https://doi.org/10.25753/BirthGrowthMJ.v30.i4.19758info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-02-26T10:09:17Zoai:repositorio.chporto.pt:10400.16/2755Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T21:20:54.011159Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Rhino-orbital-cerebral mucormycosis in a pediatric cancer patient
Mucormicose rino-orbito-cerebral num doente oncológico pediátrico
title Rhino-orbital-cerebral mucormycosis in a pediatric cancer patient
spellingShingle Rhino-orbital-cerebral mucormycosis in a pediatric cancer patient
Couto, Maria Eduarda
antifungal
encephalitis
mucormycosis
osteomyelitis
Rhizopus sp
title_short Rhino-orbital-cerebral mucormycosis in a pediatric cancer patient
title_full Rhino-orbital-cerebral mucormycosis in a pediatric cancer patient
title_fullStr Rhino-orbital-cerebral mucormycosis in a pediatric cancer patient
title_full_unstemmed Rhino-orbital-cerebral mucormycosis in a pediatric cancer patient
title_sort Rhino-orbital-cerebral mucormycosis in a pediatric cancer patient
author Couto, Maria Eduarda
author_facet Couto, Maria Eduarda
Oliva, Tereza
Alberto, Pedro
Lebre, Ana
Pinto, Armando
Ferreira, Ana Maia
author_role author
author2 Oliva, Tereza
Alberto, Pedro
Lebre, Ana
Pinto, Armando
Ferreira, Ana Maia
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico da Unidade Local de Saúde de Santo António
dc.contributor.author.fl_str_mv Couto, Maria Eduarda
Oliva, Tereza
Alberto, Pedro
Lebre, Ana
Pinto, Armando
Ferreira, Ana Maia
dc.subject.por.fl_str_mv antifungal
encephalitis
mucormycosis
osteomyelitis
Rhizopus sp
topic antifungal
encephalitis
mucormycosis
osteomyelitis
Rhizopus sp
description Aim: Mucormycosis infections are highly lethal in immunosuppressed patients. The authors present a rare case of successful treatment of the condition. Case description: A 14-year-old male with acute lymphoblastic lymphoma in remission was diagnosed with pansinusitis, cerebral osteomyelitis, and encephalitis with an abscess caused by Rhizopus sp. Neurosurgical drainage, endoscopic sinus surgery, and left eye enucleation were performed, and the patient was simultaneously treated with lipossomal-amphotericin B and posaconazol (later replaced by isavuconazol). However, complications (left frontal lobe herniation and cerebrospinal fluid fistula) ensued, requiring surgical reoperation. Chemotherapy was restarted four months later. Comments: This is a rare case report, in which early and aggressive surgery, antifungal treatment, and multidisciplinary team work were crucial for the successful outcome.
publishDate 2021
dc.date.none.fl_str_mv 2021-12
2021-12-01T00:00:00Z
2022-11-30T10:41:49Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.16/2755
url http://hdl.handle.net/10400.16/2755
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2183-9417
https://doi.org/10.25753/BirthGrowthMJ.v30.i4.19758
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833599235591766016

Registros relacionados