Avaliação do reparo ósseo frente implantação de materiais retrobturadores em alvéolos de ratas osteoporóticas

• Ano de defesa: 2015
• Autor(a) principal: Medina Junior, Antonio Carlos
• Orientador(a): Vivan, Rodrigo Ricci
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade do Sagrado Coração
• Programa de Pós-Graduação: Cirurgia Bucomaxilofacial
• Departamento: Ciências da Saúde e Biológicas
• País: Brasil
• Palavras-chave em Português: Cirurgia Parendodôntica; MTA; Sealer 26; Osteoporose; Resposta óssea
• Palavras-chave em Inglês: Apical surgery; MTA; Sealer 26; Osteoporosis; Alveolar socket response
• Área do conhecimento CNPq: CIRURGIA::CIRURGIA TRAUMATOLOGICA
• Link de acesso: http://tede2.usc.br:8080/jspui/handle/tede/287

The relationship of osteoporosis with their demonstration in oral cavity is a complex problem, being cause for a large number of experimental and clinical research. The aim of this study was to evaluate the alveolar socket response front MTA and Sealer 26 deployment in osteoporotic rats. Were used 48 female rats (Rattus novergicus albinus, Wistar), aged 90 days and weighing approximately 350 g from the vivarium of Sagrado Coração University – USC, which have undergone previous surgery of ovariectomy for induction of osteoporosis. After confirming the proposed disease induction materials used such as root-end filling materials, were implanted in the dental socket of the animals. The groups were so divided (n=6): Group I: MTA Angelus OVX; Group II: Sealer OVX 26; Group III: MTA Angelus SHAM; Group IV: Sealer 26 SHAM; Group v: empty Tube OVX; Group VI: empty Tube SHAM. The trial period was 30 and 45 days. After the trial period, the animals were killed and performed histological processing for further analysis. For intra-group comparisons, were used the Kruskal-Wallis tests and Dun. For comparisons enter-group we used the Mann-Whitney test. Finally, for the global comparison tests were used of Kruskal-Wallis and Dun. In all the analyses the significance level was set at 5 (p=0.05). The results showed that there was no statistically significant difference between the materials in the control group (SHAM) and the OVX Group (p>0.05). Also no statistically significant difference was verified among the groups (p>0.05). Based on the methodology proposed and the results of this study it can be concluded that osteoporosis did not influence on bone response against the tested materials.